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    anapc10 anaphase promoting complex subunit 10 [ Danio rerio (zebrafish) ]

    Gene ID: 798352, updated on 2-Nov-2024

    Summary

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    Official Symbol
    anapc10provided by ZNC
    Official Full Name
    anaphase promoting complex subunit 10provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060224-2
    See related
    Ensembl:ENSDARG00000090152 AllianceGenome:ZFIN:ZDB-GENE-060224-2
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to be involved in protein K11-linked ubiquitination. Predicted to act upstream of or within anaphase-promoting complex-dependent catabolic process and cell division. Predicted to be part of anaphase-promoting complex. Orthologous to human ANAPC10 (anaphase promoting complex subunit 10). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See anapc10 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (43718115..43723929)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (43916597..43922411)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene OTU deubiquitinase 4 Neighboring gene ATP-binding cassette, sub-family E (OABP), member 1 Neighboring gene uncharacterized LOC101884517 Neighboring gene GTPase IMAP family member 9

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Mettl3 Mutation Disrupts Gamete Maturation and Reduces Fertility in Zebrafish. Xia H, et al. Genetics, 2018 Feb. PMID 29196300, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within anaphase-promoting complex-dependent catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in anatomical structure morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein K11-linked ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of anaphase-promoting complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of anaphase-promoting complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    anaphase-promoting complex subunit 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001267696.1 → NP_001254625.1  anaphase-promoting complex subunit 10

      See identical proteins and their annotated locations for NP_001254625.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      EH468666, EH536941
      UniProtKB/TrEMBL
      A0A8M1NZQ3, E7FCJ1
      Related
      ENSDARP00000124965.1, ENSDART00000149503.2
      Conserved Domains (1) summary
      pfam03256
      Location:6 → 183
      ANAPC10; Anaphase-promoting complex, subunit 10 (APC10)

    2. NM_001267697.1 → NP_001254626.1  anaphase-promoting complex subunit 10

      See identical proteins and their annotated locations for NP_001254626.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      EH468666, EH548575
      UniProtKB/TrEMBL
      A0A8M1NZQ3, E7FCJ1
      Related
      ENSDARP00000123807.1, ENSDART00000149266.3
      Conserved Domains (1) summary
      pfam03256
      Location:6 → 183
      ANAPC10; Anaphase-promoting complex, subunit 10 (APC10)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      43718115..43723929
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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