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    pdik1l PDLIM1 interacting kinase 1 like [ Danio rerio (zebrafish) ]

    Gene ID: 569665, updated on 14-Nov-2024

    Summary

    Official Symbol
    pdik1lprovided by ZNC
    Official Full Name
    PDLIM1 interacting kinase 1 likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-051113-236
    See related
    Ensembl:ENSDARG00000056509 AllianceGenome:ZFIN:ZDB-GENE-051113-236
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fc95a02; zgc:123209
    Summary
    Predicted to enable eukaryotic translation initiation factor 2alpha kinase activity. Predicted to be involved in regulation of translational initiation. Predicted to act upstream of or within protein phosphorylation and regulation of autophagy. Predicted to be active in cytoplasm and nucleus. Orthologous to human PDIK1L (PDLIM1 interacting kinase 1 like). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See pdik1l in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (15485556..15517398)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (15581194..15605441)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene finTRIM family, member 55 Neighboring gene lin-28 homolog Ab Neighboring gene protein phosphatase 1, regulatory subunit 8a Neighboring gene forkhead box O6 b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC123209

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of G2/M transition of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of G2/MI transition of meiotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within regulation of autophagy IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    serine/threonine-protein kinase pdik1l
    NP_001032789.2
    XP_021323801.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037700.2NP_001032789.2  serine/threonine-protein kinase pdik1l

      Status: VALIDATED

      Source sequence(s)
      BC108040, CR936906, EG569238, EH552212
      UniProtKB/Swiss-Prot
      Q32PP3
      UniProtKB/TrEMBL
      A0A8M9PNI0, A5WV55
      Related
      ENSDARP00000073471.4, ENSDART00000079014.5
      Conserved Domains (1) summary
      cd13977
      Location:7331
      STKc_PDIK1L; Catalytic domain of the Serine/Threonine kinase, PDLIM1 interacting kinase 1 like

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      15485556..15517398
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021468126.2XP_021323801.1  serine/threonine-protein kinase pdik1l isoform X1

      UniProtKB/Swiss-Prot
      Q32PP3
      UniProtKB/TrEMBL
      A0A8M9PNI0, A5WV55
      Related
      ENSDARP00000147587.1, ENSDART00000182797.1
      Conserved Domains (1) summary
      cd13977
      Location:7331
      STKc_PDIK1L; Catalytic domain of the Serine/Threonine kinase, PDLIM1 interacting kinase 1 like