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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_008422.2 RefSeqGene
- Range
-
4867..246944
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_579
mRNA and Protein(s)
-
NM_001061.7 → NP_001052.3 thromboxane-A synthase isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes isoform 1, which is also known as isoform TXS-I. Both variants 1 and 3 encode the same isoform.
- Source sequence(s)
-
AC004914, AC004961, AC006021, KF459643
- Consensus CDS
-
CCDS5855.2
- UniProtKB/Swiss-Prot
- B4DJG6, E7EMU9, E7EP08, E7ESB5, O14987, P24557, Q16843, Q16844, Q8IUN1, Q96CN2, Q9GZW4, Q9HD77, Q9HD78, Q9HD79, Q9HD80, Q9HD81, Q9HD82, Q9HD83, Q9HD84
- UniProtKB/TrEMBL
-
Q53F23
- Related
- ENSP00000402536.3, ENST00000448866.7
- Conserved Domains (1) summary
-
- pfam00067
Location:47 → 530
- p450; Cytochrome P450
-
NM_001130966.5 → NP_001124438.2 thromboxane-A synthase isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3, also known as TXS-III) differs in the 5' UTR, compared to variant 1. Both variants 1 and 3 encode the same isoform (1, also known as isoform TXS-I).
- Source sequence(s)
-
AC006021, AK223466, BC014117
- Consensus CDS
-
CCDS5855.2
- UniProtKB/Swiss-Prot
- B4DJG6, E7EMU9, E7EP08, E7ESB5, O14987, P24557, Q16843, Q16844, Q8IUN1, Q96CN2, Q9GZW4, Q9HD77, Q9HD78, Q9HD79, Q9HD80, Q9HD81, Q9HD82, Q9HD83, Q9HD84
- UniProtKB/TrEMBL
-
Q53F23
- Related
- ENSP00000338087.7, ENST00000336425.10
- Conserved Domains (1) summary
-
- pfam00067
Location:47 → 530
- p450; Cytochrome P450
-
NM_001166253.4 → NP_001159725.2 thromboxane-A synthase isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) includes an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (3) that is longer than isoform 1.
- Source sequence(s)
-
AK296069, BM673654
- Consensus CDS
-
CCDS55174.2
- UniProtKB/TrEMBL
-
Q53F23
- Related
- ENSP00000411274.3, ENST00000458722.6
- Conserved Domains (1) summary
-
- pfam00067
Location:47 → 576
- p450; Cytochrome P450
-
NM_001166254.4 → NP_001159726.1 thromboxane-A synthase isoform 4
See identical proteins and their annotated locations for NP_001159726.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream translational start codon, compared to variant 1. The encoded isoform (4) is shorter at the N-terminus, compared to isoform 1.
- Source sequence(s)
-
AC006021, BC014117, BM673654
- Consensus CDS
-
CCDS55175.1
- UniProtKB/TrEMBL
-
Q53F23
- Related
- ENSP00000388736.1, ENST00000425687.5
- Conserved Domains (1) summary
-
- pfam00067
Location:1 → 463
- p450; Cytochrome P450
-
NM_001314028.4 → NP_001300957.1 thromboxane-A synthase isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) uses an alternate splice site in an internal exon, compared to variant 1. The resulting isoform (5) has a shorter and distinct N-terminus compared to isoform 1.
- Source sequence(s)
-
AC004914, AC006021, AK301164, BM673654
- UniProtKB/TrEMBL
-
B4DVP1
- Conserved Domains (1) summary
-
- pfam00067
Location:31 → 511
- p450; Cytochrome P450
-
NM_001366537.3 → NP_001353466.1 thromboxane-A synthase isoform 6
Status: REVIEWED
- Source sequence(s)
-
AC004914, AC004961, AC006021, KF459643
- UniProtKB/TrEMBL
-
B4DVP1
- Conserved Domains (1) summary
-
- pfam00067
Location:63 → 469
- p450; Cytochrome P450
-
NM_001366538.2 → NP_001353467.1 thromboxane-A synthase isoform 7
Status: REVIEWED
- Source sequence(s)
-
AC004914, CD367977, DC315339
- Consensus CDS
-
CCDS94215.1
- UniProtKB/TrEMBL
- A0A498U6I9, B7Z6W1, E7EP75
- Related
- ENSP00000391567.3, ENST00000455353.6
- Conserved Domains (1) summary
-
- cl12078
Location:47 → 112
- p450; Cytochrome P450
-
NM_030984.6 → NP_112246.3 thromboxane-A synthase isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2, also known as TXS-II) lacks an alternate exon in the 3' coding region that encodes the heme binding site, compared to transcript variant 1. The encoded isoform (2, also known as isoform TXS-II) lacks thromboxane A synthase activity, has a distinct C-terminus, and is shorter than isoform 1.
- Source sequence(s)
-
AC004914, AC006021, BM673654, M80646
- Consensus CDS
-
CCDS5856.2
- UniProtKB/TrEMBL
-
B4E0M5
- Related
- ENSP00000411326.3, ENST00000411653.6
- Conserved Domains (1) summary
-
- cl12078
Location:47 → 456
- p450; Cytochrome P450
RNA
-
NR_159363.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC006021, BG326666
- Related
-
ENST00000481440.5
-
NR_159364.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC006021
- Related
-
ENST00000474763.5
-
NR_159365.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC006021
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000007.14 Reference GRCh38.p14 Primary Assembly
- Range
-
139778242..140020293
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011516544.4 → XP_011514846.1 thromboxane-A synthase isoform X1
- UniProtKB/TrEMBL
-
B4E0M5
- Conserved Domains (1) summary
-
- cl12078
Location:48 → 456
- p450; Cytochrome P450
Alternate T2T-CHM13v2.0
Genomic
-
NC_060931.1 Alternate T2T-CHM13v2.0
- Range
-
141091534..141333885
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054358905.1 → XP_054214880.1 thromboxane-A synthase isoform X1
- UniProtKB/TrEMBL
-
B4E0M5