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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001281765.3 → NP_001268694.1 ephrin type-A receptor 5 isoform c
See identical proteins and their annotated locations for NP_001268694.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) represents the longest transcript and encodes the longest protein (isoform c).
- Source sequence(s)
-
AC018683, AC104137, BC136257, BX537946
- Consensus CDS
-
CCDS75133.1
- UniProtKB/TrEMBL
- B7ZKJ3, Q59FT4
- Related
- ENSP00000480763.1, ENST00000622150.4
- Conserved Domains (7) summary
-
- cd09546
Location:966 → 1031
- SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
- smart00454
Location:970 → 1028
- SAM; Sterile alpha motif
- cd10483
Location:60 → 232
- EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
- cd00063
Location:469 → 559
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd05066
Location:671 → 937
- PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
- pfam07714
Location:676 → 933
- Pkinase_Tyr; Protein tyrosine kinase
- pfam14575
Location:579 → 671
- EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
-
NM_001281766.3 → NP_001268695.1 ephrin type-A receptor 5 isoform d
See identical proteins and their annotated locations for NP_001268695.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks an alternate in-frame exon in the coding region compared to variant 3. The resulting protein (isoform d) is shorter but has the same N- and C-termini compared to isoform c.
- Source sequence(s)
-
AC018683, AC104137, BC143427, BX537946
- Consensus CDS
-
CCDS75131.1
- UniProtKB/TrEMBL
- B7ZKW7, Q59FT4
- Related
- ENSP00000478537.1, ENST00000613740.5
- Conserved Domains (7) summary
-
- cd09546
Location:944 → 1009
- SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
- smart00454
Location:948 → 1006
- SAM; Sterile alpha motif
- cd10483
Location:60 → 232
- EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
- cd00063
Location:469 → 559
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd05066
Location:649 → 915
- PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
- pfam07714
Location:654 → 911
- Pkinase_Tyr; Protein tyrosine kinase
- pfam14575
Location:579 → 649
- EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
-
NM_001281767.3 → NP_001268696.1 ephrin type-A receptor 5 isoform e
See identical proteins and their annotated locations for NP_001268696.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) includes a 3' terminal exon that extends past a splice site used in variant c, resulting in a different 3' coding region and 3' UTR. The resulting protein (isoform e) is shorter and has a distinct C-terminus compared to isoform c.
- Source sequence(s)
-
AB209375, AC018683, AC104137, BM664168, H11658
- Consensus CDS
-
CCDS75132.1
- UniProtKB/TrEMBL
- F8VP57, Q59FT4
- Related
- ENSP00000427638.1, ENST00000511294.1
- Conserved Domains (6) summary
-
- cd10483
Location:60 → 232
- EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
- cd00063
Location:469 → 559
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd05066
Location:671 → 937
- PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
- pfam00041
Location:359 → 447
- fn3; Fibronectin type III domain
- pfam14575
Location:576 → 673
- EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
- cl15755
Location:966 → 1004
- SAM_superfamily; SAM (Sterile alpha motif )
-
NM_001318761.2 → NP_001305690.1 ephrin type-A receptor 5 isoform f
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) contains an alternate exon in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 3. The resulting protein (isoform f) has a shorter N-terminus compared to isoform c.
- Source sequence(s)
-
AC018683, BC136258, BX537946
- UniProtKB/TrEMBL
-
Q59FT4
- Conserved Domains (7) summary
-
- cd09546
Location:897 → 962
- SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
- smart00454
Location:901 → 959
- SAM; Sterile alpha motif
- cd00063
Location:400 → 490
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd05066
Location:602 → 868
- PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
- pfam07714
Location:607 → 864
- Pkinase_Tyr; Protein tyrosine kinase
- pfam14575
Location:510 → 602
- EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
- cl02704
Location:1 → 163
- EphR_LBD; Ligand Binding Domain of Ephrin Receptors
-
NM_004439.8 → NP_004430.4 ephrin type-A receptor 5 isoform a
See identical proteins and their annotated locations for NP_004430.4
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) used an alternate splice site in the coding region compared to variant 3. The resulting protein (isoform a) is shorter but has the same N- and C-termini compared to isoform c.
- Source sequence(s)
-
AB209375, AC018683, AC104137, BC136257, BX537946, X95425
- Consensus CDS
-
CCDS3513.1
- UniProtKB/Swiss-Prot
- P54756, Q7Z3F2
- UniProtKB/TrEMBL
- A0A384MU00, Q59FT4
- Related
- ENSP00000273854.3, ENST00000273854.7
- Conserved Domains (6) summary
-
- cd09546
Location:965 → 1030
- SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
- cd10483
Location:60 → 232
- EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
- cd00063
Location:469 → 559
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd05066
Location:670 → 936
- PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
- pfam00041
Location:359 → 447
- fn3; Fibronectin type III domain
- pfam14575
Location:578 → 670
- EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
-
NM_182472.5 → NP_872272.2 ephrin type-A receptor 5 isoform b
See identical proteins and their annotated locations for NP_872272.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate splice site and lacks an alternate exon in the coding region compared to variant 3. The resulting protein (isoform b) is shorter but has the same N- and C-termini compared to isoform c.
- Source sequence(s)
-
AB209375, AC018683, AC104137, BC136257, BX537946, L36644, X95425
- Consensus CDS
-
CCDS3514.1
- UniProtKB/TrEMBL
-
Q59FT4
- Related
- ENSP00000346899.4, ENST00000354839.8
- Conserved Domains (7) summary
-
- cd09546
Location:943 → 1008
- SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
- smart00454
Location:947 → 1005
- SAM; Sterile alpha motif
- cd10483
Location:60 → 232
- EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
- cd00063
Location:469 → 559
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd05066
Location:648 → 914
- PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
- pfam07714
Location:653 → 910
- Pkinase_Tyr; Protein tyrosine kinase
- pfam14575
Location:578 → 648
- EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000004.12 Reference GRCh38.p14 Primary Assembly
- Range
-
65319567..65670489 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047449763.1 → XP_047305719.1 ephrin type-A receptor 5 isoform X5
- UniProtKB/TrEMBL
-
Q59FT4
-
XM_017007880.3 → XP_016863369.1 ephrin type-A receptor 5 isoform X6
- UniProtKB/TrEMBL
-
Q59FT4
-
XM_005265653.5 → XP_005265710.1 ephrin type-A receptor 5 isoform X4
- UniProtKB/TrEMBL
- F8W9W0, Q59FT4
- Related
- ENSP00000389208.2, ENST00000432638.6
- Conserved Domains (7) summary
-
- cd09546
Location:802 → 867
- SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
- smart00454
Location:806 → 864
- SAM; Sterile alpha motif
- cd10483
Location:60 → 232
- EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
- cd00063
Location:305 → 395
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd05066
Location:507 → 773
- PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
- pfam07714
Location:512 → 769
- Pkinase_Tyr; Protein tyrosine kinase
- pfam14575
Location:415 → 507
- EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
-
XM_047449762.1 → XP_047305718.1 ephrin type-A receptor 5 isoform X3
- UniProtKB/TrEMBL
-
Q59FT4
-
XM_017007878.3 → XP_016863367.1 ephrin type-A receptor 5 isoform X2
- UniProtKB/TrEMBL
-
Q59FT4
-
XM_011531735.4 → XP_011530037.1 ephrin type-A receptor 5 isoform X1
- UniProtKB/TrEMBL
-
Q59FT4
- Conserved Domains (7) summary
-
- cd09546
Location:854 → 919
- SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
- smart00454
Location:858 → 916
- SAM; Sterile alpha motif
- cd10483
Location:60 → 232
- EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
- cd00063
Location:357 → 447
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- cd05066
Location:559 → 825
- PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
- pfam07714
Location:564 → 821
- Pkinase_Tyr; Protein tyrosine kinase
- pfam14575
Location:467 → 559
- EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
-
XM_017007881.3 → XP_016863370.1 ephrin type-A receptor 5 isoform X7
- UniProtKB/TrEMBL
-
Q59FT4
Alternate T2T-CHM13v2.0
Genomic
-
NC_060928.1 Alternate T2T-CHM13v2.0
- Range
-
68756500..69108844 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054349189.1 → XP_054205164.1 ephrin type-A receptor 5 isoform X5
- UniProtKB/TrEMBL
-
Q59FT4
-
XM_054349190.1 → XP_054205165.1 ephrin type-A receptor 5 isoform X6
- UniProtKB/TrEMBL
-
Q59FT4
-
XM_054349188.1 → XP_054205163.1 ephrin type-A receptor 5 isoform X4
- UniProtKB/TrEMBL
- F8W9W0, Q59FT4
-
XM_054349187.1 → XP_054205162.1 ephrin type-A receptor 5 isoform X3
- UniProtKB/TrEMBL
-
Q59FT4
-
XM_054349186.1 → XP_054205161.1 ephrin type-A receptor 5 isoform X2
- UniProtKB/TrEMBL
-
Q59FT4
-
XM_054349185.1 → XP_054205160.1 ephrin type-A receptor 5 isoform X1
- UniProtKB/TrEMBL
-
Q59FT4
-
XM_054349191.1 → XP_054205166.1 ephrin type-A receptor 5 isoform X7
- UniProtKB/TrEMBL
-
Q59FT4