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    prorp protein only RNase P catalytic subunit [ Danio rerio (zebrafish) ]

    Gene ID: 555630, updated on 2-Nov-2024

    Summary

    Official Symbol
    prorpprovided by ZNC
    Official Full Name
    protein only RNase P catalytic subunitprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-100618-4
    See related
    Ensembl:ENSDARG00000075057 AllianceGenome:ZFIN:ZDB-GENE-100618-4
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    gb:dt074413; si:dkeyp-33b5.4
    Summary
    Predicted to enable ribonuclease P activity. Predicted to be involved in mitochondrial tRNA 5'-end processing and tRNA 5'-leader removal. Predicted to act upstream of or within tRNA processing. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial ribonuclease P complex. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 54. Orthologous to human PRORP (protein only RNase P catalytic subunit). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See prorp in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (12971304..13007284, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (12817238..12853204, complement)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b Neighboring gene proteasome 20S subunit alpha 6a Neighboring gene protein phosphatase 2, regulatory subunit B'', gamma Neighboring gene family with sequence similarity 177 member A1 Neighboring gene F-box protein 33

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ribonuclease P activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ribonuclease P activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial tRNA 5'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in tRNA 5'-leader removal IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within tRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of mitochondrial ribonuclease P complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mitochondrial ribonuclease P catalytic subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      12971304..13007284 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_678197.9XP_683289.3  mitochondrial ribonuclease P catalytic subunit

      UniProtKB/TrEMBL
      A0A8N7TCQ5, X1WBZ5
      Related
      ENSDARP00000127737.1, ENSDART00000156812.2
      Conserved Domains (2) summary
      sd00004
      Location:215237
      PPR; PPR repeat [structural motif]
      pfam16953
      Location:338574
      PRORP; Protein-only RNase P