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    wipf2a WAS/WASL interacting protein family, member 2a [ Danio rerio (zebrafish) ]

    Gene ID: 563976, updated on 2-Nov-2024

    Summary

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    Official Symbol
    wipf2aprovided by ZNC
    Official Full Name
    WAS/WASL interacting protein family, member 2aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-121219-6
    See related
    Ensembl:ENSDARG00000045298 AllianceGenome:ZFIN:ZDB-GENE-121219-6
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable actin binding activity. Orthologous to human WIPF2 (WAS/WASL interacting protein family member 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See wipf2a in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (11830380..11889874, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (11882652..11906280, complement)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene cell division cycle 6 homolog (S. cerevisiae) Neighboring gene Pim proto-oncogene, serine/threonine kinase, related 93 Neighboring gene uncharacterized LOC137490405 Neighboring gene serine/threonine-protein kinase pim-2-like Neighboring gene si:ch211-69b7.6 Neighboring gene ATP-binding cassette, sub-family C (CFTR/MRP), member 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution of JAK-STAT pathway components: mechanisms and role in immune system development. Liongue C, et al. PLoS One, 2012. PMID 22412924, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    WAS/WASL-interacting protein family member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      11830380..11889874 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068224295.1 → XP_068080396.1  WAS/WASL-interacting protein family member 2 isoform X3

    2. XM_021479753.2 → XP_021335428.1  WAS/WASL-interacting protein family member 2 isoform X2

      UniProtKB/TrEMBL
      A0A8M9Q7J7
      Conserved Domains (1) summary
      pfam02205
      Location:35 → 59
      WH2; WH2 motif

    3. XM_005155759.5 → XP_005155816.1  WAS/WASL-interacting protein family member 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B1U3, F1R8X0
      Related
      ENSDARP00000075985.5, ENSDART00000081544.6
      Conserved Domains (1) summary
      pfam02205
      Location:35 → 59
      WH2; WH2 motif
    Nucleotide Protein Strain
    Heading Accession and Version

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