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    desi1b desumoylating isopeptidase 1b [ Danio rerio (zebrafish) ]

    Gene ID: 793871, updated on 2-Nov-2024

    Summary

    Official Symbol
    desi1bprovided by ZNC
    Official Full Name
    desumoylating isopeptidase 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-936
    See related
    Ensembl:ENSDARG00000089529 AllianceGenome:ZFIN:ZDB-GENE-040426-936
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    desi2b; pppde2b; fam152bb; zgc:56199
    Summary
    Predicted to enable palmitoyl-(protein) hydrolase activity and peptidase activity. Predicted to be involved in protein export from nucleus and regulation of proteasomal ubiquitin-dependent protein catabolic process. Orthologous to human DESI1 (desumoylating isopeptidase 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See desi1b in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (18895657..18898475, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (18772471..18776638, complement)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene myocardin related transcription factor Ab Neighboring gene shisa family member 8b Neighboring gene X-ray repair complementing defective repair in Chinese hamster cells 6 Neighboring gene Josephin domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Clone Names

    • MGC56199

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables palmitoyl-(protein) hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in protein export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of proteasomal ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    desumoylating isopeptidase 1b
    Names
    PPPDE peptidase domain containing 2b
    desumoylating isopeptidase 2b
    family with sequence similarity 152, member Bb
    NP_956502.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200208.1NP_956502.1  desumoylating isopeptidase 1b

      See identical proteins and their annotated locations for NP_956502.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045987
      UniProtKB/TrEMBL
      Q7ZTH7
      Related
      ENSDARP00000108643.1, ENSDART00000121866.2
      Conserved Domains (1) summary
      pfam05903
      Location:7149
      Peptidase_C97; PPPDE putative peptidase domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      18895657..18898475 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394835.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      886336..889154 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395301.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      110695..113503 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)