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    syngr1a synaptogyrin 1a [ Danio rerio (zebrafish) ]

    Gene ID: 450047, updated on 9-Dec-2024

    Summary

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    Official Symbol
    syngr1aprovided by ZNC
    Official Full Name
    synaptogyrin 1aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041010-169
    See related
    Ensembl:ENSDARG00000002564 AllianceGenome:ZFIN:ZDB-GENE-041010-169
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    syngr1; zgc:101712
    Summary
    Predicted to be located in membrane. Predicted to be active in neuromuscular junction and synaptic vesicle membrane. Is expressed in nervous system; neural crest; optic vesicle; and pigment cell. Orthologous to human SYNGR1 (synaptogyrin 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See syngr1a in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (21251627..21280373, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (21121079..21149857, complement)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene zgc:153968 Neighboring gene titin-cap (telethonin) Neighboring gene family with sequence similarity 171 member A2a Neighboring gene integrin, alpha 2b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. SMN deficiency alters Nrxn2 expression and splicing in zebrafish and mouse models of spinal muscular atrophy. See K, et al. Hum Mol Genet, 2014 Apr 1. PMID 24218366
    2. Gene co-expression network analysis reveals mechanisms underlying ozone-induced carbamazepine toxicity in zebrafish (Danio rerio) embryos. Pohl J, et al. Chemosphere, 2021 Aug. PMID 34088109
    3. Allele-specific gene expression can underlie altered transcript abundance in zebrafish mutants. White RJ, et al. Elife, 2022 Feb 17. PMID 35175196, Free PMC Article
    4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in neuromuscular junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in synaptic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    synaptogyrin-1a
    Names
    synaptogyrin 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001006067.1 → NP_001006067.1  synaptogyrin-1a

      See identical proteins and their annotated locations for NP_001006067.1

      Status: PROVISIONAL

      Source sequence(s)
      BC083255
      UniProtKB/TrEMBL
      B2GTJ6, F6P9B9, Q5XJP3
      Related
      ENSDARP00000005611.6, ENSDART00000003939.7
      Conserved Domains (1) summary
      pfam01284
      Location:19 → 166
      MARVEL; Membrane-associating domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      21251627..21280373 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005171578.5 → XP_005171635.1  synaptogyrin-1a isoform X1

      UniProtKB/TrEMBL
      A0A8M2BIW4
      Conserved Domains (1) summary
      pfam01284
      Location:19 → 166
      MARVEL; Membrane-associating domain
    Nucleotide Protein
    Heading Accession and Version

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