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    sstr5 somatostatin receptor 5 [ Danio rerio (zebrafish) ]

    Gene ID: 406588, updated on 2-Nov-2024

    Summary

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    Official Symbol
    sstr5provided by ZNC
    Official Full Name
    somatostatin receptor 5provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2502
    See related
    Ensembl:ENSDARG00000101655 AllianceGenome:ZFIN:ZDB-GENE-040426-2502
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:85682
    Summary
    Predicted to enable neuropeptide binding activity and somatostatin receptor activity. Predicted to be involved in cellular response to glucocorticoid stimulus; neuropeptide signaling pathway; and regulation of insulin secretion. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in neuron projection and plasma membrane. Human ortholog(s) of this gene implicated in bipolar disorder. Orthologous to human SSTR5 (somatostatin receptor 5). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See sstr5 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (11101552..11122914)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (11135010..11156371)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein S7 Neighboring gene MIF4G domain containing b Neighboring gene butyrophilin-like protein 8 Neighboring gene uncharacterized LOC110438747

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables neuropeptide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables somatostatin receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables somatostatin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cellular response to glucocorticoid stimulus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in neuropeptide signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of insulin secretion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    somatostatin receptor type 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213297.1 → NP_998462.1  somatostatin receptor type 5

      See identical proteins and their annotated locations for NP_998462.1

      Status: PROVISIONAL

      Source sequence(s)
      BC068356
      UniProtKB/TrEMBL
      Q6NV10
      Related
      ENSDARP00000132886.1, ENSDART00000172103.2
      Conserved Domains (2) summary
      pfam00001
      Location:51 → 300
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:42 → 241
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      11101552..11122914
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005164434.5 → XP_005164491.1  somatostatin receptor type 5 isoform X2

      UniProtKB/TrEMBL
      A0A8M2BBL8
      Conserved Domains (2) summary
      pfam00001
      Location:51 → 300
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:42 → 241
      7tm_4; Olfactory receptor

    2. XM_005164433.4 → XP_005164490.1  somatostatin receptor type 5 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BBV6
      Conserved Domains (2) summary
      pfam00001
      Location:51 → 300
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:42 → 241
      7tm_4; Olfactory receptor

    RNA

    1. XR_011008169.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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