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    apol apolipoprotein L [ Danio rerio (zebrafish) ]

    Gene ID: 798813, updated on 9-Dec-2024

    Summary

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    Official Symbol
    apolprovided by ZNC
    Official Full Name
    apolipoprotein Lprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-120215-22
    See related
    Ensembl:ENSDARG00000073718 AllianceGenome:ZFIN:ZDB-GENE-120215-22
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch73-233k15.2
    Summary
    Predicted to enable lipid binding activity. Predicted to act upstream of or within lipid transport and lipoprotein metabolic process. Predicted to be located in extracellular region. Orthologous to human APOL1 (apolipoprotein L1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See apol in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (29673728..29688485, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (29543458..29557691, complement)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 3, subunit D Neighboring gene sulfotransferase family 3, cytosolic sulfotransferase 1 Neighboring gene GTPase IMAP family member 4 Neighboring gene uncharacterized LOC110437798 Neighboring gene uncharacterized LOC101886115 Neighboring gene uncharacterized LOC137490615 Neighboring gene calcium channel, voltage-dependent, gamma subunit 2a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. IRF2 Cooperates with Phosphoprotein of Spring Viremia of Carp Virus to Suppress Antiviral Response in Zebrafish. Huang W, et al. J Virol, 2022 Nov 23. PMID 36314827, Free PMC Article
    2. IFN-Stimulated Genes in Zebrafish and Humans Define an Ancient Arsenal of Antiviral Immunity. Levraud JP, et al. J Immunol, 2019 Dec 15. PMID 31732531
    3. Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes. Briolat V, et al. J Immunol, 2014 May 1. PMID 24683187
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables lipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within lipid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within lipoprotein metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    apolipoprotein L4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      29673728..29688485 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001339206.9 → XP_001339242.2  apolipoprotein L4

      UniProtKB/TrEMBL
      A0A8M1Q7F0, I3ISX5
      Related
      ENSDARP00000126025.1, ENSDART00000151679.2
      Conserved Domains (1) summary
      pfam05461
      Location:257 → 538
      ApoL; Apolipoprotein L
    Nucleotide Protein Strain
    Heading Accession and Version

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