derl1 derlin 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: derl1provided by ZNC
Official Full Name: derlin 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2793
See related: Ensembl:ENSDARG00000021905 AllianceGenome:ZFIN:ZDB-GENE-040426-2793
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:55637; wu:fb09d07; wu:fb94d05; wu:fj92g12
Summary: Predicted to enable signal recognition particle binding activity. Predicted to be involved in ERAD pathway and endoplasmic reticulum unfolded protein response. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in liver. Orthologous to human DERL1 (derlin 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (25642936..25663844, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (25727904..25748812, complement)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb09d07.x1 (e-PCR)
- UniSTS:202778

fb94d05.x1 (e-PCR)
- UniSTS:203555

fj92g12.x1 (e-PCR)
- UniSTS:200349

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables signal recognition particle binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in ERAD pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in endoplasmic reticulum unfolded protein response	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: derlin-1

Names: Der1-like domain family, member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.