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    ppp1r13ba protein phosphatase 1, regulatory subunit 13Ba [ Danio rerio (zebrafish) ]

    Gene ID: 563577, updated on 14-Nov-2024

    Summary

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    Official Symbol
    ppp1r13baprovided by ZNC
    Official Full Name
    protein phosphatase 1, regulatory subunit 13Baprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-9805
    See related
    Ensembl:ENSDARG00000004377 AllianceGenome:ZFIN:ZDB-GENE-030131-9805
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb375; fc63g02; fc76b12; sb:cb375; wu:fa02c01; wu:fb69g10; wu:fc63g02; wu:fc76b12; si:ch73-9j13.1
    Summary
    Predicted to enable p53 binding activity. Predicted to act upstream of or within regulation of apoptotic process. Predicted to be active in nucleus. Is expressed in several structures, including cardiovascular system; hematopoietic system; musculature system; nervous system; and neural tube. Orthologous to human PPP1R13B (protein phosphatase 1 regulatory subunit 13B). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See ppp1r13ba in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (14614137..14691622, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (14606207..14683703, complement)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene dishevelled associated activator of morphogenesis 1a Neighboring gene serine dehydratase-like Neighboring gene protein tyrosine phosphatase 4A2a Neighboring gene gap junction protein beta 9a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Retinoic acid receptor subtype-specific transcriptotypes in the early zebrafish embryo. Samarut E, et al. Mol Endocrinol, 2014 Feb. PMID 24422634, Free PMC Article
    2. Identification of vascular and hematopoietic genes downstream of etsrp by deep sequencing in zebrafish. Gomez G, et al. PLoS One, 2012. PMID 22438865, Free PMC Article
    3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables p53 binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein phosphatase 1, regulatory subunit 13Ba

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001204257.1 → NP_001191186.1  protein phosphatase 1, regulatory subunit 13Ba

      Status: VALIDATED

      Source sequence(s)
      CU469548, FP067407
      UniProtKB/TrEMBL
      A0A8M1P3N6, F1RDT1
      Related
      ENSDARP00000028707.7, ENSDART00000037371.8
      Conserved Domains (5) summary
      cd00204
      Location:906 → 1029
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:912 → 1003
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:912 → 938
      ANK; ANK repeat [structural motif]
      cl09111
      Location:240 → 368
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
      cl17036
      Location:1042 → 1098
      SH3; Src Homology 3 domain superfamily

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      14614137..14691622 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009292888.4 → XP_009291163.1  protein phosphatase 1, regulatory subunit 13Ba isoform X2

      UniProtKB/TrEMBL
      A0A8M3AU31
      Conserved Domains (5) summary
      cd00204
      Location:878 → 1001
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:884 → 975
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:884 → 910
      ANK; ANK repeat [structural motif]
      cl09111
      Location:212 → 340
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
      cl17036
      Location:1014 → 1070
      SH3; Src Homology 3 domain superfamily

    2. XM_009292889.4 → XP_009291164.1  protein phosphatase 1, regulatory subunit 13Ba isoform X3

      UniProtKB/TrEMBL
      A0A8M3AR73
      Conserved Domains (5) summary
      cd00204
      Location:873 → 996
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:879 → 970
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:879 → 905
      ANK; ANK repeat [structural motif]
      cl09111
      Location:247 → 375
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
      cl17036
      Location:1009 → 1065
      SH3; Src Homology 3 domain superfamily

    3. XM_009292887.4 → XP_009291162.1  protein phosphatase 1, regulatory subunit 13Ba isoform X1

      UniProtKB/TrEMBL
      A0A8M3AJN6
      Conserved Domains (5) summary
      cd00204
      Location:913 → 1036
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:919 → 1010
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:919 → 945
      ANK; ANK repeat [structural motif]
      cl09111
      Location:247 → 375
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
      cl17036
      Location:1049 → 1105
      SH3; Src Homology 3 domain superfamily

    4. XM_009292890.3 → XP_009291165.1  protein phosphatase 1, regulatory subunit 13Ba isoform X4

      UniProtKB/TrEMBL
      A0A8M3AIS3
      Conserved Domains (5) summary
      cd00204
      Location:802 → 925
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:808 → 899
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:808 → 834
      ANK; ANK repeat [structural motif]
      cl09111
      Location:136 → 264
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
      cl17036
      Location:938 → 994
      SH3; Src Homology 3 domain superfamily

    5. XM_068214420.1 → XP_068070521.1  protein phosphatase 1, regulatory subunit 13Ba isoform X6

    6. XM_009292891.4 → XP_009291166.1  protein phosphatase 1, regulatory subunit 13Ba isoform X5

      UniProtKB/TrEMBL
      A0A8M3B283
      Conserved Domains (5) summary
      cd00204
      Location:797 → 920
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:803 → 894
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:803 → 829
      ANK; ANK repeat [structural motif]
      cl09111
      Location:131 → 259
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
      cl17036
      Location:933 → 989
      SH3; Src Homology 3 domain superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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