pfn2a profilin 2a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pfn2aprovided by ZNC
Official Full Name: profilin 2aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-34
See related: Ensembl:ENSDARG00000012682 AllianceGenome:ZFIN:ZDB-GENE-030131-34
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: pfn2l; zgc:86790; hm:zeh0341; wu:fb02e10; wu:fi35b08
Summary: Predicted to enable actin binding activity. Predicted to be involved in positive regulation of actin filament bundle assembly and regulation of actin filament polymerization. Predicted to act upstream of or within actin cytoskeleton organization. Predicted to be active in cytoplasm. Orthologous to human PFN2 (profilin 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 2

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (10147103..10151839)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (10349215..10354019)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fi35b08.x1 (e-PCR)
- UniSTS:204561

fc81f04.y1 (e-PCR)
- UniSTS:194588

fc60b02.y1 (e-PCR)
- UniSTS:194149

fb02e10.x1 (e-PCR)
- UniSTS:202672

fc05a09.y1 (e-PCR)
- UniSTS:192192

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables actin binding	IBA Inferred from Biological aspect of Ancestor more info
enables actin binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within actin cytoskeleton organization	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of actin filament bundle assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of actin filament polymerization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: profilin 2a

Names: profilin 2 like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.