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    slc25a17 solute carrier family 25 member 17 [ Danio rerio (zebrafish) ]

    Gene ID: 100093708, updated on 9-Dec-2024

    Summary

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    Official Symbol
    slc25a17provided by ZNC
    Official Full Name
    solute carrier family 25 member 17provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070620-4
    See related
    AllianceGenome:ZFIN:ZDB-GENE-070620-4
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:162641; si:dkey-68o6.9
    Summary
    Enables AMP transmembrane transporter activity and coenzyme A transmembrane transporter activity. Acts upstream of or within AMP transport; nucleotide transmembrane transport; and swim bladder development. Predicted to be located in membrane. Predicted to be active in peroxisomal membrane. Is expressed in gut; head; and swim bladder. Orthologous to human SLC25A17 (solute carrier family 25 member 17). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: suggests misassembly
    Orthologs
    human mouse all
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    Genomic context

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    See slc25a17 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (24681835..24692452)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (24551287..24561904)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene zmp:0000001062 Neighboring gene GTPase IMAP family member 7 Neighboring gene myocardin related transcription factor Aa Neighboring gene protein shisa-8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. nudt7 gene depletion causes transcriptomic change in early development of zebrafish. Bhandari S, et al. J Biochem, 2022 Dec 27. PMID 36270274
    2. Slc25a17 acts as a peroxisomal coenzyme A transporter and regulates multiorgan development in zebrafish. Kim YI, et al. J Cell Physiol, 2020 Jan. PMID 31187491
    3. Targeted Gene Expression in Zebrafish Exposed to Chlorpyrifos-Oxon Confirms Phenotype-Specific Mechanisms Leading to Adverse Outcomes. Garcia-Reyero N, et al. Bull Environ Contam Toxicol, 2016 Jun. PMID 27086301, Free PMC Article
    4. Insights Into the Peroxisomal Protein Inventory of Zebrafish. Kamoshita M, et al. Front Physiol, 2022. PMID 35295584, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Slc25a17 acts as a peroxisomal coenzyme A transporter and regulates multiorgan development in zebrafish.
      Title: Slc25a17 acts as a peroxisomal coenzyme A transporter and regulates multiorgan development in zebrafish.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables AMP transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables coenzyme A transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within swim bladder development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    peroxisomal membrane protein PMP34
    Names
    peroxisomal membrane protein PMP34-like
    solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein), member 17
    solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001099261.2 → NP_001092731.2  peroxisomal membrane protein PMP34

      Status: VALIDATED

      Source sequence(s)
      BC139873, BX569789
      UniProtKB/TrEMBL
      A0A8M1NDU0, A5D6T2
      Conserved Domains (1) summary
      pfam00153
      Location:104 → 202
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      24681835..24692452
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394532.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      158989..169920
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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