dcaf13 ddb1 and cul4 associated factor 13 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: dcaf13provided by ZNC
Official Full Name: ddb1 and cul4 associated factor 13provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-703
See related: Ensembl:ENSDARG00000002267 AllianceGenome:ZFIN:ZDB-GENE-040426-703
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wdsof1; zgc:55391
Summary: Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and oocyte growth. Predicted to act upstream of or within ribosome biogenesis. Predicted to be located in nucleus. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex and small-subunit processome. Predicted to be active in nucleolus. Orthologous to human DCAF13 (DDB1 and CUL4 associated factor 13). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (44653266..44673805, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (44686550..44707089, complement)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info
enables ubiquitin-like ligase-substrate adaptor activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA Inferred from Biological aspect of Ancestor more info
involved_in oocyte growth	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within rRNA processing	IEA Inferred from Electronic Annotation more info
involved_in rRNA processing	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within ribosome biogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of Cul4-RING E3 ubiquitin ligase complex	ISS Inferred from Sequence or Structural Similarity more info
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
part_of small-subunit processome	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: DDB1- and CUL4-associated factor 13

Names: WD repeat and SOF domain-containing protein 1; WD repeats and SOF1 domain containing

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200129.1 → NP_956423.1 DDB1- and CUL4-associated factor 13

See identical proteins and their annotated locations for NP_956423.1

Status: PROVISIONAL

Source sequence(s)

BC044155

UniProtKB/Swiss-Prot

Q803X4

UniProtKB/TrEMBL

B2GQH5

Related

ENSDARP00000028109.7, ENSDART00000015139.8

Conserved Domains (4) summary

COG2319
Location:49 → 349

WD40; WD40 repeat [General function prediction only]

cd00200
Location:59 → 353

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

pfam04158
Location:354 → 438

Sof1; Sof1-like domain

sd00039
Location:113 → 155

7WD40; WD40 repeat [structural motif]