coq2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: coq2provided by ZNC
Official Full Name: coenzyme Q2 4-hydroxybenzoate polyprenyltransferaseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-070410-84
See related: Ensembl:ENSDARG00000059510 AllianceGenome:ZFIN:ZDB-GENE-070410-84
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:162600
Summary: Predicted to enable 4-hydroxybenzoate polyprenyltransferase activity. Predicted to be involved in ubiquinone biosynthetic process. Predicted to be located in membrane and mitochondrion. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 1. Orthologous to human COQ2 (coenzyme Q2, polyprenyltransferase). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (66203053..66215504, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (65523950..65536399, complement)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fk57a09.x1 (e-PCR)
- UniSTS:201216

fb23b05.x1 (e-PCR)
- UniSTS:190317

fb23b05.x1 (e-PCR)
- UniSTS:190318

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 4-hydroxybenzoate polyprenyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables 4-hydroxybenzoate polyprenyltransferase activity	IEA Inferred from Electronic Annotation more info
enables prenyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity, transferring alkyl or aryl (other than methyl) groups	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within isoprenoid biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in isoprenoid biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in ubiquinone biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within ubiquinone biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in ubiquinone biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrial inner membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: 4-hydroxybenzoate polyprenyltransferase, mitochondrial

Names: coenzyme Q2 homolog, prenyltransferase

NP_001082955.1

EC 2.5.1.39

XP_068077150.1

EC 2.5.1.39

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.