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    LINC01550 long intergenic non-protein coding RNA 1550 [ Homo sapiens (human) ]

    Gene ID: 388011, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC01550provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 1550provided by HGNC
    Primary source
    HGNC:HGNC:20111
    See related
    Ensembl:ENSG00000246223 AllianceGenome:HGNC:20111
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C14orf64
    Expression
    Broad expression in skin (RPKM 2.3), lymph node (RPKM 1.7) and 22 other tissues See more
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    Genomic context

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    See LINC01550 in Genome Data Viewer
    Location:
    14q32.2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (97925610..97978124, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (92158116..92210608, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (98391947..98444461, complement)

    Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 2291 Neighboring gene uncharacterized LOC124903377 Neighboring gene uncharacterized LOC105370650 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9001 Neighboring gene uncharacterized LOC105370651 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr14:98178659-98179858 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr14:98213528-98214158 Neighboring gene long intergenic non-protein coding RNA 2312 Neighboring gene ReSE screen-validated silencer GRCh37_chr14:98315519-98315728 Neighboring gene ReSE screen-validated silencer GRCh37_chr14:98334809-98334984 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:98415455-98415954 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:98444461-98444960 Neighboring gene uncharacterized LOC107984706 Neighboring gene uncharacterized LOC105370655 Neighboring gene uncharacterized LOC105370654

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Long noncoding RNA LINC01550 inhibits colorectal cancer malignancy by suppressing the Wnt/β-catenin signaling pathway. Wu W, et al. J Biochem Mol Toxicol, 2024 Aug. PMID 39041324
    2. Elevated LINC01550 induces the apoptosis and cell cycle arrest of melanoma. Chen J, et al. Med Oncol, 2021 Feb 20. PMID 33609219
    3. MIMT1 and LINC01550 are uncharted lncRNAs down-regulated in colorectal cancer. Vejdandoust F, et al. Int J Exp Pathol, 2023 Jun. PMID 36727289, Free PMC Article
    4. Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis. Zhao SX, et al. Hum Mol Genet, 2013 Aug 15. PMID 23612905
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Long noncoding RNA LINC01550 inhibits colorectal cancer malignancy by suppressing the Wnt/beta-catenin signaling pathway.
      Title: Long noncoding RNA LINC01550 inhibits colorectal cancer malignancy by suppressing the Wnt/β-catenin signaling pathway.
    2. MIMT1 and LINC01550 are uncharted lncRNAs down-regulated in colorectal cancer.
      Title: MIMT1 and LINC01550 are uncharted lncRNAs down-regulated in colorectal cancer.
    3. Elevated LINC01550 induces the apoptosis and cell cycle arrest of melanoma.
      Title: Elevated LINC01550 induces the apoptosis and cell cycle arrest of melanoma.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_015430.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL352981, KF456003

    2. NR_152746.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL352981
      Related
      ENST00000502187.6

    3. NR_152747.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL352981
      Related
      ENST00000512901.6

    4. NR_152748.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL352981

    5. NR_152749.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL352981
      Related
      ENST00000652825.1

    6. NR_152750.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL352981
      Related
      ENST00000556462.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

      Range
      97925610..97978124 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060938.1 Alternate T2T-CHM13v2.0

      Range
      92158116..92210608 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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