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    GSE1 Gse1 coiled-coil protein [ Homo sapiens (human) ]

    Gene ID: 23199, updated on 9-Dec-2024

    Summary

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    Official Symbol
    GSE1provided by HGNC
    Official Full Name
    Gse1 coiled-coil proteinprovided by HGNC
    Primary source
    HGNC:HGNC:28979
    See related
    Ensembl:ENSG00000131149 MIM:616886; AllianceGenome:HGNC:28979
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CRHSP24; KIAA0182
    Summary
    This gene encodes a proline-rich protein with coiled coil domains that may be a subunit of a BRAF35-HDAC (BHC) histone deacetylase complex. This gene may function as an oncogene in breast cancer and enhanced expression of the encoded protein has been observed in breast cancer patients. [provided by RefSeq, May 2017]
    Expression
    Ubiquitous expression in placenta (RPKM 7.8), fat (RPKM 7.8) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See GSE1 in Genome Data Viewer
    Location:
    16q24.1
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (85169512..85676200)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (91235680..91741713)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (85645015..85709806)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371381 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85159272-85159794 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85159795-85160316 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85170709-85171641 Neighboring gene uncharacterized LOC105371382 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85180218-85180762 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85180763-85181307 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7800 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7801 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11264 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85187102-85187602 Neighboring gene Sharpr-MPRA regulatory region 15454 Neighboring gene long intergenic non-protein coding RNA 2139 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85204591-85205300 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85205301-85206012 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85221161-85222101 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85224026-85224526 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr16:85233339-85234538 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85234576-85235312 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85240619-85241362 Neighboring gene Sharpr-MPRA regulatory region 3131 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85248283-85248783 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85254771-85255472 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85255473-85256172 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:85259454-85259616 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11265 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11266 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11267 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85261597-85262172 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:85267436-85267602 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85267685-85268542 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7802 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7803 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85272407-85272982 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85274317-85275021 Neighboring gene microRNA 12128 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85292757-85293460 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85293461-85294165 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85292052-85292756 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85300159-85300706 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85303550-85304252 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85305185-85306181 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85308847-85309819 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85309820-85310793 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85310794-85311766 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:85330200-85330435 Neighboring gene Sharpr-MPRA regulatory region 9478 Neighboring gene uncharacterized LOC101928502 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11270 Neighboring gene Sharpr-MPRA regulatory region 9835 Neighboring gene uncharacterized LOC107984830 Neighboring gene long intergenic non-protein coding RNA 311 Neighboring gene cytochrome c oxidase subunit 6C pseudogene 16 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7804 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85350968-85351763 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85353355-85353865 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85353866-85354375 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85355126-85355656 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85355657-85356187 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85361388-85361956 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85361957-85362524 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85364231-85364798 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:85380301-85380577 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85383235-85383873 Neighboring gene microRNA 5093 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85387813-85388516 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85388517-85389218 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85389454-85389954 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85397928-85398554 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85398555-85399181 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:85404333-85404558 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85406218-85406731 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85418551-85419116 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr16:85429961-85430526 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr16:85429395-85429960 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85436783-85437311 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85451929-85452546 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85453670-85454511 Neighboring gene Sharpr-MPRA regulatory region 8888 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85468128-85468788 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85469448-85470107 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85470108-85470766 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85474018-85474538 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85474539-85475058 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85477805-85478693 Neighboring gene uncharacterized LOC124903738 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7806 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr16:85485239-85485738 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85485752-85486252 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85491854-85492505 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85494556-85495263 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85493849-85494555 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr16:85493140-85493848 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85496679-85497386 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85498095-85498800 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85507767-85508622 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85508623-85509477 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:85522312-85522482 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85523747-85524594 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85524595-85525442 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85525443-85526290 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11271 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85547643-85548327 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85548328-85549011 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85549012-85549696 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85549697-85550379 Neighboring gene uncharacterized LOC124903739 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85557842-85558457 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85558458-85559072 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85559689-85560304 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85575513-85576422 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85578183-85579016 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85580527-85581027 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85583771-85584359 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85584360-85584947 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7807 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7808 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:85588705-85589205 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11272 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7809 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85590477-85591335 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:85592721-85592911 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11273 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11274 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85598712-85599441 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:85601775-85601970 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85600901-85601628 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11275 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11276 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11277 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85610162-85610728 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85611294-85611859 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85613556-85614120 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85616579-85617188 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85617189-85617800 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85617801-85618411 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85619023-85619633 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85618412-85619022 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85621594-85622550 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85623933-85624848 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85632946-85633646 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85634349-85635068 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85635069-85635787 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85635788-85636506 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85638229-85638872 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7810 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85644485-85645006 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85645007-85645528 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7812 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11280 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7813 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85647861-85648712 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7815 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7814 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11281 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85652369-85653040 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85653041-85653712 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85658570-85659078 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85659079-85659586 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85660095-85660601 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85660691-85661510 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85661511-85662329 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85665311-85666088 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85668961-85669914 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85672914-85673448 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85673449-85673981 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85685005-85685906 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:85704698-85704871 Neighboring gene RNA, 7SL, cytoplasmic 381, pseudogene Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85721369-85721902 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7818 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85722953-85723454 Neighboring gene uncharacterized LOC124903740 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7817 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85729233-85729805 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:85735359-85735574 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85738821-85739513 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85743177-85743746 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85762391-85763258 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11282 Neighboring gene GINS complex subunit 2 Neighboring gene chromosome 16 open reading frame 74 Neighboring gene microRNA 1910

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Overexpression of GSE1 Related to Trastuzumab Resistance in Gastric Cancer Cells. Wang W, et al. Biomed Res Int, 2021. PMID 33623790, Free PMC Article
    2. GSE1 promotes the proliferation and migration of lung adenocarcinoma cells by downregulating KLF6 expression. Meng Z, et al. Cell Biol Int, 2024 Oct. PMID 38886911
    3. GSE1 negative regulation by miR-489-5p promotes breast cancer cell proliferation and invasion. Chai P, et al. Biochem Biophys Res Commun, 2016 Feb 26. PMID 26828271
    4. GSE1 links the HDAC1/CoREST co-repressor complex to DNA damage. Vcelkova T, et al. Nucleic Acids Res, 2023 Nov 27. PMID 37878419, Free PMC Article
    5. GSE1 predicts poor survival outcome in gastric cancer patients by SLC7A5 enhancement of tumor growth and metastasis. Ding K, et al. J Biol Chem, 2018 Mar 16. PMID 29367342, Free PMC Article

    See all (87) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. GSE1 promotes the proliferation and migration of lung adenocarcinoma cells by downregulating KLF6 expression.
      Title: GSE1 promotes the proliferation and migration of lung adenocarcinoma cells by downregulating KLF6 expression.
    2. GSE1 links the HDAC1/CoREST co-repressor complex to DNA damage.
      Title: GSE1 links the HDAC1/CoREST co-repressor complex to DNA damage.
    3. Overexpression of GSE1 Related to Trastuzumab Resistance in Gastric Cancer Cells.
      Title: Overexpression of GSE1 Related to Trastuzumab Resistance in Gastric Cancer Cells.
    4. High GSE1 expression is associated with gastric cancer growth and metastasis.
      Title: GSE1 predicts poor survival outcome in gastric cancer patients by SLC7A5 enhancement of tumor growth and metastasis.
    5. In this study, we reported that GSE1 is overexpression in breast cancer and silencing of GSE1 significantly suppressed breast cancer cells proliferation, migration and invasion.
      Title: GSE1 negative regulation by miR-489-5p promotes breast cancer cell proliferation and invasion.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • KIAA0182

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    genetic suppressor element 1
    Names
    CTC-786C10.1
    Gse1 coiled-coil protein homolog

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_054715.1 RefSeqGene

      Range
      448811..511689
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001134473.3 → NP_001127945.1  genetic suppressor element 1 isoform 2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) contains an alternate 5' terminal exon, lacks an exon in the 5' region, and initiates translation from an in-frame downstream AUG, compared to variant 1. The resulting isoform (2) has a shorter N-terminus compared to isoform 1.
      Source sequence(s)
      AC123908, BC037556, D80004, GD138010
      Consensus CDS
      CCDS45539.1
      UniProtKB/TrEMBL
      H0Y613
      Related
      ENSP00000384839.2, ENST00000405402.6
      Conserved Domains (2) summary
      pfam12540
      Location:628 → 768
      DUF3736; Protein of unknown function (DUF3736)
      pfam16716
      Location:1038 → 1096
      BST2; Bone marrow stromal antigen 2

    2. NM_001278184.3 → NP_001265113.1  genetic suppressor element 1 isoform 3

      See identical proteins and their annotated locations for NP_001265113.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) lacks an in-frame exon in the 5' coding region compared to variant 1, which results in a shorter isoform (3) missing an internal protein segment compared to isoform 1.
      Source sequence(s)
      AC123908, BC037556, D80004, GD138010, HY041236
      Consensus CDS
      CCDS62007.1
      UniProtKB/TrEMBL
      H0Y613
      Related
      ENSP00000376934.1, ENST00000393243.5
      Conserved Domains (2) summary
      pfam12540
      Location:659 → 799
      DUF3736; Protein of unknown function (DUF3736)
      pfam16716
      Location:1069 → 1127
      BST2; Bone marrow stromal antigen 2

    3. NM_014615.5 → NP_055430.1  genetic suppressor element 1 isoform 1

      See identical proteins and their annotated locations for NP_055430.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AC123908, BC037556, D80004, GD138010, HY041236
      Consensus CDS
      CCDS10952.1
      UniProtKB/Swiss-Prot
      D3DUM4, Q14687, Q8IY61, Q96GA4, Q9BW09
      UniProtKB/TrEMBL
      H0Y613
      Related
      ENSP00000253458.6, ENST00000253458.12
      Conserved Domains (2) summary
      pfam12540
      Location:732 → 872
      DUF3736; Protein of unknown function (DUF3736)
      pfam16716
      Location:1142 → 1200
      BST2; Bone marrow stromal antigen 2

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

      Range
      85169512..85676200
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047433837.1 → XP_047289793.1  genetic suppressor element 1 isoform X20

      UniProtKB/TrEMBL
      A0A1B0GUL3
      Related
      ENSP00000490157.1, ENST00000637419.1

    2. XM_017023084.2 → XP_016878573.1  genetic suppressor element 1 isoform X21

    3. XM_005255859.6 → XP_005255916.3  genetic suppressor element 1 isoform X1

    4. XM_005255860.4 → XP_005255917.3  genetic suppressor element 1 isoform X2

    5. XM_005255861.6 → XP_005255918.3  genetic suppressor element 1 isoform X3

    6. XM_011522965.4 → XP_011521267.1  genetic suppressor element 1 isoform X4

      Conserved Domains (2) summary
      pfam12540
      Location:768 → 908
      DUF3736; Protein of unknown function (DUF3736)
      pfam16716
      Location:1178 → 1236
      BST2; Bone marrow stromal antigen 2

    7. XM_047433828.1 → XP_047289784.1  genetic suppressor element 1 isoform X12

      UniProtKB/TrEMBL
      H0Y613

    8. XM_005255863.5 → XP_005255920.1  genetic suppressor element 1 isoform X7

      UniProtKB/TrEMBL
      H0Y613
      Conserved Domains (2) summary
      pfam12540
      Location:744 → 884
      DUF3736; Protein of unknown function (DUF3736)
      pfam16716
      Location:1154 → 1212
      BST2; Bone marrow stromal antigen 2

    9. XM_047433831.1 → XP_047289787.1  genetic suppressor element 1 isoform X15

      UniProtKB/TrEMBL
      H0Y613

    10. XM_047433823.1 → XP_047289779.1  genetic suppressor element 1 isoform X10

      UniProtKB/TrEMBL
      H0Y613

    11. XM_047433821.1 → XP_047289777.1  genetic suppressor element 1 isoform X10

      UniProtKB/TrEMBL
      H0Y613

    12. XM_047433836.1 → XP_047289792.1  genetic suppressor element 1 isoform X18

      UniProtKB/TrEMBL
      H0Y613

    13. XM_005255864.5 → XP_005255921.1  genetic suppressor element 1 isoform X8

      UniProtKB/TrEMBL
      H0Y613
      Conserved Domains (2) summary
      pfam12540
      Location:742 → 882
      DUF3736; Protein of unknown function (DUF3736)
      pfam16716
      Location:1152 → 1210
      BST2; Bone marrow stromal antigen 2

    14. XM_047433827.1 → XP_047289783.1  genetic suppressor element 1 isoform X11

      UniProtKB/TrEMBL
      H0Y613

    15. XM_005255865.5 → XP_005255922.1  genetic suppressor element 1 isoform X16

      UniProtKB/TrEMBL
      H0Y613
      Conserved Domains (2) summary
      pfam12540
      Location:669 → 809
      DUF3736; Protein of unknown function (DUF3736)
      pfam16716
      Location:1079 → 1137
      BST2; Bone marrow stromal antigen 2

    16. XM_047433832.1 → XP_047289788.1  genetic suppressor element 1 isoform X17

      UniProtKB/TrEMBL
      H0Y613

    17. XM_047433820.1 → XP_047289776.1  genetic suppressor element 1 isoform X9

      UniProtKB/TrEMBL
      H0Y613

    18. XM_047433830.1 → XP_047289786.1  genetic suppressor element 1 isoform X14

      UniProtKB/TrEMBL
      H0Y613

    19. XM_047433822.1 → XP_047289778.1  genetic suppressor element 1 isoform X10

      UniProtKB/TrEMBL
      H0Y613

    20. XM_047433824.1 → XP_047289780.1  genetic suppressor element 1 isoform X10

      UniProtKB/TrEMBL
      H0Y613

    21. XM_047433833.1 → XP_047289789.1  genetic suppressor element 1 isoform X18

      UniProtKB/TrEMBL
      H0Y613

    22. XM_011522966.4 → XP_011521268.1  genetic suppressor element 1 isoform X10

      UniProtKB/TrEMBL
      H0Y613
      Conserved Domains (2) summary
      pfam12540
      Location:729 → 869
      DUF3736; Protein of unknown function (DUF3736)
      pfam16716
      Location:1139 → 1197
      BST2; Bone marrow stromal antigen 2

    23. XM_047433826.1 → XP_047289782.1  genetic suppressor element 1 isoform X10

      UniProtKB/TrEMBL
      H0Y613

    24. XM_047433829.1 → XP_047289785.1  genetic suppressor element 1 isoform X13

      UniProtKB/TrEMBL
      H0Y613

    25. XM_047433835.1 → XP_047289791.1  genetic suppressor element 1 isoform X19

      UniProtKB/TrEMBL
      H0Y613
      Related
      ENSP00000402367.1, ENST00000412692.5

    26. XM_047433834.1 → XP_047289790.1  genetic suppressor element 1 isoform X18

      UniProtKB/TrEMBL
      H0Y613

    27. XM_047433818.1 → XP_047289774.1  genetic suppressor element 1 isoform X5

    28. XM_047433819.1 → XP_047289775.1  genetic suppressor element 1 isoform X6

    RNA

    1. XR_001751877.2 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060940.1 Alternate T2T-CHM13v2.0

      Range
      91235680..91741713
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054379897.1 → XP_054235872.1  genetic suppressor element 1 isoform X20

      UniProtKB/TrEMBL
      A0A1B0GUL3

    2. XM_047446670.1 → XP_047302626.1  genetic suppressor element 1 isoform X21

    3. XM_054379874.1 → XP_054235849.1  genetic suppressor element 1 isoform X1

    4. XM_054379875.1 → XP_054235850.1  genetic suppressor element 1 isoform X2

    5. XM_054379876.1 → XP_054235851.1  genetic suppressor element 1 isoform X3

    6. XM_054379877.1 → XP_054235852.1  genetic suppressor element 1 isoform X4

    7. XM_054379890.1 → XP_054235865.1  genetic suppressor element 1 isoform X12

      UniProtKB/TrEMBL
      H0Y613

    8. XM_054379880.1 → XP_054235855.1  genetic suppressor element 1 isoform X7

      UniProtKB/TrEMBL
      H0Y613

    9. XM_054379889.1 → XP_054235864.1  genetic suppressor element 1 isoform X15

      UniProtKB/TrEMBL
      H0Y613

    10. XM_054379884.1 → XP_054235859.1  genetic suppressor element 1 isoform X10

      UniProtKB/TrEMBL
      H0Y613

    11. XM_054379881.1 → XP_054235856.1  genetic suppressor element 1 isoform X8

      UniProtKB/TrEMBL
      H0Y613

    12. XM_054379886.1 → XP_054235861.1  genetic suppressor element 1 isoform X11

      UniProtKB/TrEMBL
      H0Y613

    13. XM_054379891.1 → XP_054235866.1  genetic suppressor element 1 isoform X16

      UniProtKB/TrEMBL
      H0Y613

    14. XM_054379892.1 → XP_054235867.1  genetic suppressor element 1 isoform X17

      UniProtKB/TrEMBL
      H0Y613

    15. XM_054379893.1 → XP_054235868.1  genetic suppressor element 1 isoform X10

      UniProtKB/TrEMBL
      H0Y613

    16. XM_054379882.1 → XP_054235857.1  genetic suppressor element 1 isoform X9

      UniProtKB/TrEMBL
      H0Y613

    17. XM_054379888.1 → XP_054235863.1  genetic suppressor element 1 isoform X14

      UniProtKB/TrEMBL
      H0Y613

    18. XM_054379883.1 → XP_054235858.1  genetic suppressor element 1 isoform X10

      UniProtKB/TrEMBL
      H0Y613

    19. XM_054379885.1 → XP_054235860.1  genetic suppressor element 1 isoform X10

      UniProtKB/TrEMBL
      H0Y613

    20. XM_054379894.1 → XP_054235869.1  genetic suppressor element 1 isoform X18

      UniProtKB/TrEMBL
      H0Y613

    21. XM_054379887.1 → XP_054235862.1  genetic suppressor element 1 isoform X13

      UniProtKB/TrEMBL
      H0Y613

    22. XM_054379896.1 → XP_054235871.1  genetic suppressor element 1 isoform X19

      UniProtKB/TrEMBL
      H0Y613

    23. XM_054379895.1 → XP_054235870.1  genetic suppressor element 1 isoform X18

      UniProtKB/TrEMBL
      H0Y613

    24. XM_054379878.1 → XP_054235853.1  genetic suppressor element 1 isoform X5

    25. XM_054379879.1 → XP_054235854.1  genetic suppressor element 1 isoform X6

    RNA

    1. XR_007086738.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q14687.3 GenPept UniProtKB/Swiss-Prot:Q14687

    Gene LinkOut

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