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    ZNF205-AS1 ZNF205 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 81854, updated on 28-Oct-2024

    Summary

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    Official Symbol
    ZNF205-AS1provided by HGNC
    Official Full Name
    ZNF205 antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:28586
    See related
    AllianceGenome:HGNC:28586
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Ubiquitous expression in ovary (RPKM 1.1), thyroid (RPKM 1.0) and 25 other tissues See more
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    Genomic context

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    See ZNF205-AS1 in Genome Data Viewer
    Location:
    16p13.3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (3110460..3115598, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (3136943..3142081, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (3160461..3165599, complement)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:3139191-3139721 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:3140253-3140782 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:3142715-3143302 Neighboring gene zinc finger and SCAN domain containing 10 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7113 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10300 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7114 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:3151352-3152052 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:3154929-3155612 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:3155613-3156296 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7117 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7118 Neighboring gene uncharacterized LOC124903629 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:3163522-3164110 Neighboring gene zinc finger protein 205 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:3174278-3174547 Neighboring gene ZNF213 antisense RNA 1 (head to head) Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr16:3177693-3178243 Neighboring gene Sharpr-MPRA regulatory region 2057 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10304 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10305 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7119 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:3188465-3188965 Neighboring gene zinc finger protein 213

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. A positive feedback loop between ZNF205-AS1 and EGR4 promotes non-small cell lung cancer growth. He S, et al. J Cell Mol Med, 2019 Feb. PMID 30556283, Free PMC Article
    2. A proteome-scale map of the human interactome network. Rolland T, et al. Cell, 2014 Nov 20. PMID 25416956, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Clone Names

    • MGC1912, MGC3771

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    involved_in SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of signal recognition particle, endoplasmic reticulum targeting IEA
    Inferred from Electronic Annotation
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_024166.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the more predominant transcript.
      Source sequence(s)
      AC108134, BC001824, BC121099, BC121100

    2. NR_024167.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses a different acceptor splice site at an internal exon, resulting in a slightly shorter transcript (by 5 nt) compared to transcript variant 1.
      Source sequence(s)
      AC108134, BC001824, BC121099, BC121100

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

      Range
      3110460..3115598 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060940.1 Alternate T2T-CHM13v2.0

      Range
      3136943..3142081 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_030970.1: Suppressed sequence

      Description
      NM_030970.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Research Materials