Cfap161 cilia and flagella associated protein 161 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Cfap161provided by MGI
Official Full Name: cilia and flagella associated protein 161provided by MGI
Primary source: MGI:MGI:1922806
See related: Ensembl:ENSMUSG00000011154 AllianceGenome:MGI:1922806
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 1700026D08Rik
Summary: Involved in flagellated sperm motility. Is active in axonemal A tubule inner sheath and sperm flagellum. Is expressed in several structures, including brain; genitourinary system; lung; node; and sensory organ. Orthologous to human CFAP161 (cilia and flagella associated protein 161). [provided by Alliance of Genome Resources, Oct 2024]
Expression: Biased expression in testis adult (RPKM 6.8) and ovary adult (RPKM 0.3) See more
Orthologs: human all
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Genomic context

Location:: 7 D3; 7 47.74 cM

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (83424820..83447528, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (83775612..83798025, complement)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

1700026D08Rik is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia.
Title: Tissue expression patterns identify mouse cilia genes.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (3)
Targeted (2) 1 citation

General gene information

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Markers

AW047638 (e-PCR)
- UniSTS:165536

NoName (e-PCR)
- UniSTS:235705

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in cilium assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in flagellated sperm motility	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in axonemal A tubule inner sheath	IDA Inferred from Direct Assay more info	PubMed
located_in axonemal microtubule	ISO Inferred from Sequence Orthology more info
located_in axonemal microtubule	ISS Inferred from Sequence or Structural Similarity more info
is_active_in motile cilium	IBA Inferred from Biological aspect of Ancestor more info
is_active_in sperm flagellum	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: cilia- and flagella-associated protein 161

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.