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    ZNF185 zinc finger protein 185 with LIM domain [ Homo sapiens (human) ]

    Gene ID: 7739, updated on 2-Nov-2024

    Summary

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    Official Symbol
    ZNF185provided by HGNC
    Official Full Name
    zinc finger protein 185 with LIM domainprovided by HGNC
    Primary source
    HGNC:HGNC:12976
    See related
    Ensembl:ENSG00000147394 MIM:300381; AllianceGenome:HGNC:12976
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    SCELL
    Summary
    Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This gene encodes a LIM-domain zinc finger protein. The LIM domain is composed of two contiguous zinc finger domains, separated by a two-amino acid residue hydrophobic linker. The LIM domain mediates protein:protein interactions. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, May 2010]
    Expression
    Biased expression in esophagus (RPKM 112.2), skin (RPKM 20.8) and 4 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See ZNF185 in Genome Data Viewer
    Location:
    Xq28
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (152898067..152973481)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (151164487..151239920)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (152066611..152142025)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 21058 Neighboring gene ReSE screen-validated silencer GRCh37_chrX:152010347-152010520 Neighboring gene centrin 2 Neighboring gene NAD(P) dependent steroid dehydrogenase-like Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:152065863-152066363 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:152070232-152070754 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:152072629-152073160 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 30028 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:152084281-152084854 Neighboring gene uncharacterized LOC124905237 Neighboring gene uncharacterized LOC105373372 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 30029 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 30030 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 30031 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 30032 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:152158397-152158896 Neighboring gene PNMA family member 5 Neighboring gene paraneoplastic antigen Ma6F-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Transcriptional silencing of zinc finger protein 185 identified by expression profiling is associated with prostate cancer progression. Vanaja DK, et al. Cancer Res, 2003 Jul 15. PMID 12873976
    2. ZNF185, an actin-cytoskeleton-associated growth inhibitory LIM protein in prostate cancer. Zhang JS, et al. Oncogene, 2007 Jan 4. PMID 16799630
    3. ZNF185 inhibits growth and invasion of lung adenocarcinoma cells through inhibition of the akt/gsk3β pathway. Wang J, et al. J Biol Regul Homeost Agents, 2016 Jul-Sep. PMID 27655485
    4. [Expression and localization of zinc finger protein 185 in sperm cells, Leydig cells and Sertoli cells of mouse testis]. You X, et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi, 2016 Oct. PMID 27667456
    5. Genomic structure of a novel LIM domain gene (ZNF185) in Xq28 and comparisons with the orthologous murine transcript. Heiss NS, et al. Genomics, 1997 Aug 1. PMID 9268636

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ZNF185 prevents stress fiber formation through the inhibition of RhoA in endothelial cells.
      Title: ZNF185 prevents stress fiber formation through the inhibition of RhoA in endothelial cells.
    2. UBE3A activates the NOTCH pathway and promotes esophageal cancer progression by degradation of ZNF185.
      Title: UBE3A activates the NOTCH pathway and promotes esophageal cancer progression by degradation of ZNF185.
    3. These data highlight the involvement of ZNF185 and cytoskeleton changes in p53-mediated cellular response to genotoxic stress and indicate ZNF185 as potential biomarker for epithelial cancer diagnosis.
      Title: ZNF185 is a p53 target gene following DNA damage.
    4. Results provide evidence that ZNF185 is a key component of the p63-dependent transcriptional program for stratified epithelial development and tissue homeostasis. ZNF185 deregulation, beyond deregulating cell adhesion in general, is also relevant for carcinoma formation of the stratified epithelia suggesting that ZNF185 may be a potential biomarker for squamous cell carcinoma diagnosis and prognosis.
      Title: ZNF185 is a p63 target gene critical for epidermal differentiation and squamous cell carcinoma development.
    5. ZNF185 was mainly distributed in the cytoplasm of Leydig cells and Sertoli cells, as well as the head and tail of sperm cells.
      Title: [Expression and localization of zinc finger protein 185 in sperm cells, Leydig cells and Sertoli cells of mouse testis].
    6. ZNF185 expression was significantly downregulated in lung adenocarcinoma tissues compared with the adjacent non-cancerous tissues and negatively correlated with lymphatic metastasis. ZNF185 overexpression inhibits the growth and invasion of LAC cells through inhibition of the AKT/GSK3beta signaling.
      Title: ZNF185 inhibits growth and invasion of lung adenocarcinoma cells through inhibition of the akt/gsk3β pathway.
    7. Transcriptional silencing of ZNF185 by methylation in prostate tumor tissues implicates the ZNF185 gene in prostate tumorigenesis.
      Title: Transcriptional silencing of zinc finger protein 185 identified by expression profiling is associated with prostate cancer progression.
    8. ZNF185 may function as a tumor-suppressor protein by associating with the actin-cytoskeleton
      Title: ZNF185, an actin-cytoskeleton-associated growth inhibitory LIM protein in prostate cancer.
    9. transcriptional activation of ZNF185 and CYP3A4 is mediated by direct association of BRG1 with their promoters and a decreased level of ZNF185 is a common feature of lung tumours
      Title: Transcriptional targets of the chromatin-remodelling factor SMARCA4/BRG1 in lung cancer cells.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See Variation Viewer (GRCh37.p13)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables zinc ion binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 185
    Names
    P1-A
    sciellin like
    zinc finger protein 185 (LIM domain)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_021255.3 RefSeqGene

      Range
      5002..80409
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178106.1 → NP_001171577.1  zinc finger protein 185 isoform 1

      See identical proteins and their annotated locations for NP_001171577.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes isoform 1.
      Source sequence(s)
      AK056517, BQ923456, DC305824, DQ508025, DQ508026
      Consensus CDS
      CCDS55529.1
      UniProtKB/Swiss-Prot
      O15231
      UniProtKB/TrEMBL
      B3KPM4
      Related
      ENSP00000440847.1, ENST00000535861.6
      Conserved Domains (1) summary
      smart00132
      Location:660 → 716
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3

    2. NM_001178107.1 → NP_001171578.1  zinc finger protein 185 isoform 2

      See identical proteins and their annotated locations for NP_001171578.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon in the CDS, as compared to variant 1. The resulting isoform (2) lacks an internal segment, as compared to isoform 1.
      Source sequence(s)
      AK056517, BQ923456, DC305824, DQ508024, DQ508026
      Consensus CDS
      CCDS55530.1
      UniProtKB/Swiss-Prot
      O15231
      UniProtKB/TrEMBL
      B3KPM4
      Related
      ENSP00000444367.1, ENST00000539731.6
      Conserved Domains (1) summary
      smart00132
      Location:631 → 687
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3

    3. NM_001178108.2 → NP_001171579.1  zinc finger protein 185 isoform 3

      See identical proteins and their annotated locations for NP_001171579.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) has additional 3 nts in one splice site and lacks two consecutive in-frame exons in another splice junction in the CDS, as compared to variant 1. The resulting isoform (3) has additional one aa in one region and lacks an internal segment in another region, as compared to isoform 1.
      Source sequence(s)
      U82671
      Consensus CDS
      CCDS55528.1
      UniProtKB/Swiss-Prot
      O15231
      UniProtKB/TrEMBL
      B3KPM4
      Related
      ENSP00000395228.2, ENST00000449285.6
      Conserved Domains (2) summary
      smart00132
      Location:629 → 685
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3
      PRK07764
      Location:178 → 517
      PRK07764; DNA polymerase III subunits gamma and tau; Validated

    4. NM_001178109.1 → NP_001171580.1  zinc finger protein 185 isoform 5

      See identical proteins and their annotated locations for NP_001171580.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) lacks two in-frame exons in the CDS, as compared to variant 1. The resulting isoform (5) lacks two internal segments, as compared to isoform 1.
      Source sequence(s)
      AK056517, BQ923456, DC305824, DQ508024
      UniProtKB/Swiss-Prot
      O15231
      UniProtKB/TrEMBL
      B3KPM4
      Conserved Domains (1) summary
      smart00132
      Location:599 → 655
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3

    5. NM_001178110.1 → NP_001171581.1  zinc finger protein 185 isoform 6

      See identical proteins and their annotated locations for NP_001171581.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) lacks two consecutive in-frame exons in one region and an in-frame exon in another region in the CDS, as compared to variant 1. The resulting isoform (6) lacks two internal segments, as compared to isoform 1.
      Source sequence(s)
      AK056517, BQ923456, DC305824, DQ508023
      Consensus CDS
      CCDS55531.1
      UniProtKB/Swiss-Prot
      O15231
      UniProtKB/TrEMBL
      B3KPM4
      Related
      ENSP00000312782.7, ENST00000318504.12
      Conserved Domains (1) summary
      smart00132
      Location:569 → 625
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3

    6. NM_001178113.2 → NP_001171584.1  zinc finger protein 185 isoform 7

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR and has multiple differences in the 5' coding region including a downstream in-frame AUG start codon, as compared to variant 1. The resulting isoform (7) has a much shorter N-terminus and an additional aa in one region, and lacks three segments in other regions, as compared to isoform 1.
      Source sequence(s)
      AK056517, AK301530, BQ923456, DQ508023, U82671
      Consensus CDS
      CCDS55532.1
      UniProtKB/TrEMBL
      H0Y704
      Related
      ENSP00000313919.8, ENST00000318529.13
      Conserved Domains (1) summary
      smart00132
      Location:407 → 463
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3

    7. NM_001178115.2 → NP_001171586.1  zinc finger protein 185 isoform 9

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) lacks multiple 5' eons, but has an alternate 5' exon, as compared to variant 1. The resulting isoform (9) is much shorter and has a different N-terminus, as compared to isoform 1.
      Source sequence(s)
      AK056517, AK095258, BQ923456, DA882423
      Consensus CDS
      CCDS69832.1
      UniProtKB/Swiss-Prot
      O15231
      UniProtKB/TrEMBL
      B3KPM4
      Related
      ENSP00000392984.2, ENST00000454925.1
      Conserved Domains (1) summary
      smart00132
      Location:266 → 322
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3

    8. NM_001388432.2 → NP_001375361.1  zinc finger protein 185 isoform 3

      Status: REVIEWED

      Source sequence(s)
      U82671
      Consensus CDS
      CCDS55528.1
      Conserved Domains (2) summary
      smart00132
      Location:629 → 685
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3
      PRK07764
      Location:178 → 517
      PRK07764; DNA polymerase III subunits gamma and tau; Validated

    9. NM_001395254.1 → NP_001382183.1  zinc finger protein 185 isoform 10

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11) represents the longest transcript and encodes the longest isoform (10).
      Source sequence(s)
      U82671
      Consensus CDS
      CCDS94691.1
      UniProtKB/TrEMBL
      A0A8Q3WKR1
      Related
      ENSP00000512166.1, ENST00000695776.1
      Conserved Domains (1) summary
      smart00132
      Location:661 → 717
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3

    10. NM_007150.3 → NP_009081.2  zinc finger protein 185 isoform 4

      See identical proteins and their annotated locations for NP_009081.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) lacks an in-frame exon in the CDS, as compared to variant 1. The resulting isoform (4) lacks an internal segment, as compared to isoform 1.
      Source sequence(s)
      AK056517, AY997296, BQ923456, DC347990
      Consensus CDS
      CCDS48184.1
      UniProtKB/Swiss-Prot
      A4FTV3, A6NME5, B4DLE9, B7Z771, B8K2L9, B8K2M0, B8K2M1, B8K2M2, E9PFR6, F5GXF7, F5GZL4, F8W8V7, H0Y4M8, O00345, O15231, Q8N1R8, Q9NSD2
      Related
      ENSP00000359291.4, ENST00000370268.8
      Conserved Domains (1) summary
      smart00132
      Location:628 → 684
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      152898067..152973481
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017029822.3 → XP_016885311.1  zinc finger protein 185 isoform X3

    2. XM_047442496.1 → XP_047298452.1  zinc finger protein 185 isoform X25

    3. XM_017029821.2 → XP_016885310.1  zinc finger protein 185 isoform X3

    4. XM_011531195.2 → XP_011529497.1  zinc finger protein 185 isoform X30

      Conserved Domains (1) summary
      smart00132
      Location:595 → 651
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3

    5. XM_017029828.2 → XP_016885317.1  zinc finger protein 185 isoform X9

    6. XM_047442501.1 → XP_047298457.1  zinc finger protein 185 isoform X36

    7. XM_017029832.2 → XP_016885321.1  zinc finger protein 185 isoform X15

    8. XM_011531194.2 → XP_011529496.1  zinc finger protein 185 isoform X28

      Conserved Domains (1) summary
      smart00132
      Location:596 → 652
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3

    9. XM_017029825.2 → XP_016885314.1  zinc finger protein 185 isoform X6

    10. XM_047442490.1 → XP_047298446.1  zinc finger protein 185 isoform X16

    11. XM_017029830.2 → XP_016885319.1  zinc finger protein 185 isoform X12

    12. XM_047442495.1 → XP_047298451.1  zinc finger protein 185 isoform X24

    13. XM_047442506.1 → XP_047298462.1  zinc finger protein 185 isoform X42

    14. XM_047442500.1 → XP_047298456.1  zinc finger protein 185 isoform X35

    15. XM_017029826.2 → XP_016885315.1  zinc finger protein 185 isoform X7

    16. XM_047442491.1 → XP_047298447.1  zinc finger protein 185 isoform X17

    17. XM_017029831.2 → XP_016885320.1  zinc finger protein 185 isoform X13

    18. XM_005274740.3 → XP_005274797.1  zinc finger protein 185 isoform X25

      Conserved Domains (1) summary
      smart00132
      Location:599 → 655
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3

    19. XM_047442507.1 → XP_047298463.1  zinc finger protein 185 isoform X43

    20. XM_017029829.2 → XP_016885318.1  zinc finger protein 185 isoform X11

    21. XM_047442493.1 → XP_047298449.1  zinc finger protein 185 isoform X21

    22. XM_047442504.1 → XP_047298460.1  zinc finger protein 185 isoform X40

    23. XM_017029834.2 → XP_016885323.1  zinc finger protein 185 isoform X19

    24. XM_005274744.3 → XP_005274801.1  zinc finger protein 185 isoform X33

      Conserved Domains (1) summary
      smart00132
      Location:570 → 626
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3

    25. XM_047442509.1 → XP_047298465.1  zinc finger protein 185 isoform X44

    26. XM_047442503.1 → XP_047298459.1  zinc finger protein 185 isoform X39

    27. XM_017029823.2 → XP_016885312.1  zinc finger protein 185 isoform X4

    28. XM_047442488.1 → XP_047298444.1  zinc finger protein 185 isoform X10

    29. XM_005274738.3 → XP_005274795.1  zinc finger protein 185 isoform X18

      See identical proteins and their annotated locations for XP_005274795.1

      UniProtKB/Swiss-Prot
      A4FTV3, A6NME5, B4DLE9, B7Z771, B8K2L9, B8K2M0, B8K2M1, B8K2M2, E9PFR6, F5GXF7, F5GZL4, F8W8V7, H0Y4M8, O00345, O15231, Q8N1R8, Q9NSD2
      Conserved Domains (1) summary
      smart00132
      Location:628 → 684
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3

    30. XM_047442502.1 → XP_047298458.1  zinc finger protein 185 isoform X37

    31. XM_047442497.1 → XP_047298453.1  zinc finger protein 185 isoform X29

    32. XM_005274741.3 → XP_005274798.1  zinc finger protein 185 isoform X26

      See identical proteins and their annotated locations for XP_005274798.1

      UniProtKB/Swiss-Prot
      O15231
      Conserved Domains (1) summary
      smart00132
      Location:599 → 655
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3

    33. XM_017029827.2 → XP_016885316.1  zinc finger protein 185 isoform X8

    34. XM_047442489.1 → XP_047298445.1  zinc finger protein 185 isoform X14

    35. XM_005274742.3 → XP_005274799.1  zinc finger protein 185 isoform X27

      Conserved Domains (1) summary
      smart00132
      Location:598 → 654
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3

    36. XM_017029835.2 → XP_016885324.1  zinc finger protein 185 isoform X23

    37. XM_005274745.3 → XP_005274802.1  zinc finger protein 185 isoform X34

      See identical proteins and their annotated locations for XP_005274802.1

      UniProtKB/Swiss-Prot
      O15231
      Conserved Domains (1) summary
      smart00132
      Location:569 → 625
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3

    38. XM_047442505.1 → XP_047298461.1  zinc finger protein 185 isoform X41

    39. XM_017029824.2 → XP_016885313.1  zinc finger protein 185 isoform X5

    40. XM_047442494.1 → XP_047298450.1  zinc finger protein 185 isoform X22

    41. XM_047442498.1 → XP_047298454.1  zinc finger protein 185 isoform X31

    42. XM_047442492.1 → XP_047298448.1  zinc finger protein 185 isoform X20

    43. XM_047442499.1 → XP_047298455.1  zinc finger protein 185 isoform X32

    44. XM_017029833.2 → XP_016885322.1  zinc finger protein 185 isoform X1

    45. XM_005274746.4 → XP_005274803.1  zinc finger protein 185 isoform X38

      Conserved Domains (1) summary
      smart00132
      Location:542 → 598
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3

    46. XM_047442508.1 → XP_047298464.1  zinc finger protein 185 isoform X2

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_025791818.1 Reference GRCh38.p14 PATCHES

      Range
      513257..588671
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054333348.1 → XP_054189323.1  zinc finger protein 185 isoform X3

    2. XM_054333373.1 → XP_054189348.1  zinc finger protein 185 isoform X25

    3. XM_054333347.1 → XP_054189322.1  zinc finger protein 185 isoform X3

    4. XM_054333378.1 → XP_054189353.1  zinc finger protein 185 isoform X30

    5. XM_054333354.1 → XP_054189329.1  zinc finger protein 185 isoform X9

    6. XM_054333384.1 → XP_054189359.1  zinc finger protein 185 isoform X36

    7. XM_054333361.1 → XP_054189336.1  zinc finger protein 185 isoform X15

    8. XM_054333376.1 → XP_054189351.1  zinc finger protein 185 isoform X28

    9. XM_054333351.1 → XP_054189326.1  zinc finger protein 185 isoform X6

    10. XM_054333362.1 → XP_054189337.1  zinc finger protein 185 isoform X16

    11. XM_054333358.1 → XP_054189333.1  zinc finger protein 185 isoform X12

    12. XM_054333371.1 → XP_054189346.1  zinc finger protein 185 isoform X24

    13. XM_054333390.1 → XP_054189365.1  zinc finger protein 185 isoform X42

    14. XM_054333383.1 → XP_054189358.1  zinc finger protein 185 isoform X35

    15. XM_054333352.1 → XP_054189327.1  zinc finger protein 185 isoform X7

    16. XM_054333363.1 → XP_054189338.1  zinc finger protein 185 isoform X17

    17. XM_054333359.1 → XP_054189334.1  zinc finger protein 185 isoform X13

    18. XM_054333372.1 → XP_054189347.1  zinc finger protein 185 isoform X25

    19. XM_054333391.1 → XP_054189366.1  zinc finger protein 185 isoform X43

    20. XM_054333357.1 → XP_054189332.1  zinc finger protein 185 isoform X11

    21. XM_054333368.1 → XP_054189343.1  zinc finger protein 185 isoform X21

    22. XM_054333388.1 → XP_054189363.1  zinc finger protein 185 isoform X40

    23. XM_054333366.1 → XP_054189341.1  zinc finger protein 185 isoform X19

    24. XM_054333381.1 → XP_054189356.1  zinc finger protein 185 isoform X33

    25. XM_054333392.1 → XP_054189367.1  zinc finger protein 185 isoform X44

    26. XM_054333387.1 → XP_054189362.1  zinc finger protein 185 isoform X39

    27. XM_054333349.1 → XP_054189324.1  zinc finger protein 185 isoform X4

    28. XM_054333356.1 → XP_054189331.1  zinc finger protein 185 isoform X45

    29. XM_054333355.1 → XP_054189330.1  zinc finger protein 185 isoform X10

    30. XM_054333365.1 → XP_054189340.1  zinc finger protein 185 isoform X18

      UniProtKB/Swiss-Prot
      A4FTV3, A6NME5, B4DLE9, B7Z771, B8K2L9, B8K2M0, B8K2M1, B8K2M2, E9PFR6, F5GXF7, F5GZL4, F8W8V7, H0Y4M8, O00345, O15231, Q8N1R8, Q9NSD2

    31. XM_054333385.1 → XP_054189360.1  zinc finger protein 185 isoform X37

    32. XM_054333377.1 → XP_054189352.1  zinc finger protein 185 isoform X29

    33. XM_054333364.1 → XP_054189339.1  zinc finger protein 185 isoform X46

    34. XM_054333374.1 → XP_054189349.1  zinc finger protein 185 isoform X26

    35. XM_054333353.1 → XP_054189328.1  zinc finger protein 185 isoform X8

    36. XM_054333360.1 → XP_054189335.1  zinc finger protein 185 isoform X14

    37. XM_054333375.1 → XP_054189350.1  zinc finger protein 185 isoform X27

    38. XM_054333370.1 → XP_054189345.1  zinc finger protein 185 isoform X23

    39. XM_054333382.1 → XP_054189357.1  zinc finger protein 185 isoform X34

    40. XM_054333389.1 → XP_054189364.1  zinc finger protein 185 isoform X41

    41. XM_054333350.1 → XP_054189325.1  zinc finger protein 185 isoform X5

    42. XM_054333369.1 → XP_054189344.1  zinc finger protein 185 isoform X22

    43. XM_054333379.1 → XP_054189354.1  zinc finger protein 185 isoform X31

    44. XM_054333367.1 → XP_054189342.1  zinc finger protein 185 isoform X20

    45. XM_054333380.1 → XP_054189355.1  zinc finger protein 185 isoform X32

    46. XM_054333386.1 → XP_054189361.1  zinc finger protein 185 isoform X38

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      151164487..151239920
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054327809.1 → XP_054183784.1  zinc finger protein 185 isoform X3

    2. XM_054327835.1 → XP_054183810.1  zinc finger protein 185 isoform X25

    3. XM_054327808.1 → XP_054183783.1  zinc finger protein 185 isoform X3

    4. XM_054327840.1 → XP_054183815.1  zinc finger protein 185 isoform X30

    5. XM_054327815.1 → XP_054183790.1  zinc finger protein 185 isoform X9

    6. XM_054327846.1 → XP_054183821.1  zinc finger protein 185 isoform X36

    7. XM_054327822.1 → XP_054183797.1  zinc finger protein 185 isoform X15

    8. XM_054327838.1 → XP_054183813.1  zinc finger protein 185 isoform X28

    9. XM_054327812.1 → XP_054183787.1  zinc finger protein 185 isoform X6

    10. XM_054327823.1 → XP_054183798.1  zinc finger protein 185 isoform X16

    11. XM_054327819.1 → XP_054183794.1  zinc finger protein 185 isoform X12

    12. XM_054327833.1 → XP_054183808.1  zinc finger protein 185 isoform X24

    13. XM_054327852.1 → XP_054183827.1  zinc finger protein 185 isoform X42

    14. XM_054327845.1 → XP_054183820.1  zinc finger protein 185 isoform X35

    15. XM_054327813.1 → XP_054183788.1  zinc finger protein 185 isoform X7

    16. XM_054327824.1 → XP_054183799.1  zinc finger protein 185 isoform X17

    17. XM_054327820.1 → XP_054183795.1  zinc finger protein 185 isoform X13

    18. XM_054327834.1 → XP_054183809.1  zinc finger protein 185 isoform X25

    19. XM_054327853.1 → XP_054183828.1  zinc finger protein 185 isoform X43

    20. XM_054327818.1 → XP_054183793.1  zinc finger protein 185 isoform X11

    21. XM_054327830.1 → XP_054183805.1  zinc finger protein 185 isoform X21

    22. XM_054327850.1 → XP_054183825.1  zinc finger protein 185 isoform X40

    23. XM_054327828.1 → XP_054183803.1  zinc finger protein 185 isoform X19

    24. XM_054327843.1 → XP_054183818.1  zinc finger protein 185 isoform X33

    25. XM_054327855.1 → XP_054183830.1  zinc finger protein 185 isoform X44

    26. XM_054327849.1 → XP_054183824.1  zinc finger protein 185 isoform X39

    27. XM_054327810.1 → XP_054183785.1  zinc finger protein 185 isoform X4

    28. XM_054327817.1 → XP_054183792.1  zinc finger protein 185 isoform X45

    29. XM_054327816.1 → XP_054183791.1  zinc finger protein 185 isoform X10

    30. XM_054327826.1 → XP_054183801.1  zinc finger protein 185 isoform X18

      UniProtKB/Swiss-Prot
      A4FTV3, A6NME5, B4DLE9, B7Z771, B8K2L9, B8K2M0, B8K2M1, B8K2M2, E9PFR6, F5GXF7, F5GZL4, F8W8V7, H0Y4M8, O00345, O15231, Q8N1R8, Q9NSD2

    31. XM_054327847.1 → XP_054183822.1  zinc finger protein 185 isoform X37

    32. XM_054327839.1 → XP_054183814.1  zinc finger protein 185 isoform X29

    33. XM_054327825.1 → XP_054183800.1  zinc finger protein 185 isoform X46

    34. XM_054327836.1 → XP_054183811.1  zinc finger protein 185 isoform X26

    35. XM_054327814.1 → XP_054183789.1  zinc finger protein 185 isoform X8

    36. XM_054327821.1 → XP_054183796.1  zinc finger protein 185 isoform X14

    37. XM_054327837.1 → XP_054183812.1  zinc finger protein 185 isoform X27

    38. XM_054327832.1 → XP_054183807.1  zinc finger protein 185 isoform X23

    39. XM_054327844.1 → XP_054183819.1  zinc finger protein 185 isoform X34

    40. XM_054327851.1 → XP_054183826.1  zinc finger protein 185 isoform X41

    41. XM_054327811.1 → XP_054183786.1  zinc finger protein 185 isoform X5

    42. XM_054327831.1 → XP_054183806.1  zinc finger protein 185 isoform X22

    43. XM_054327841.1 → XP_054183816.1  zinc finger protein 185 isoform X31

    44. XM_054327829.1 → XP_054183804.1  zinc finger protein 185 isoform X20

    45. XM_054327842.1 → XP_054183817.1  zinc finger protein 185 isoform X32

    46. XM_054327827.1 → XP_054183802.1  zinc finger protein 185 isoform X1

    47. XM_054327848.1 → XP_054183823.1  zinc finger protein 185 isoform X38

    48. XM_054327854.1 → XP_054183829.1  zinc finger protein 185 isoform X2

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001178114.1: Suppressed sequence

      Description
      NM_001178114.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript, which uses a poorly supported non-consensus splice site.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O15231.3 GenPept UniProtKB/Swiss-Prot:O15231

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