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    ANKRD6 ankyrin repeat domain 6 [ Homo sapiens (human) ]

    Gene ID: 22881, updated on 27-Nov-2024

    Summary

    Official Symbol
    ANKRD6provided by HGNC
    Official Full Name
    ankyrin repeat domain 6provided by HGNC
    Primary source
    HGNC:HGNC:17280
    See related
    Ensembl:ENSG00000135299 MIM:610583; AllianceGenome:HGNC:17280
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Predicted to be involved in negative regulation of canonical Wnt signaling pathway and positive regulation of JNK cascade. Predicted to act upstream of or within positive regulation of Wnt signaling pathway, planar cell polarity pathway. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in brain (RPKM 8.1), ovary (RPKM 5.5) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ANKRD6 in Genome Data Viewer
    Location:
    6q15
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (89433152..89633834)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (90642513..90843208)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (90142871..90343553)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24824 Neighboring gene Sharpr-MPRA regulatory region 13381 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24826 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:90084816-90085316 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:90085317-90085817 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24827 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24828 Neighboring gene Ras related GTP binding D Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17392 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17393 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17394 Neighboring gene uncharacterized LOC124901360 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17395 Neighboring gene MPRA-validated peak5952 silencer Neighboring gene NACA pseudogene 7 Neighboring gene RNA, 7SL, cytoplasmic 11, pseudogene Neighboring gene uncharacterized LOC105377889 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:90262750-90263251 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr6:90265242-90265742 Neighboring gene uncharacterized LOC124901359 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:90319101-90319300 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr6:90347214-90348413 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr6:90367565-90368764 Neighboring gene MDN1 antisense RNA 1 Neighboring gene Sharpr-MPRA regulatory region 852 Neighboring gene LYR motif containing 2 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:90399309-90399858 Neighboring gene midasin AAA ATPase 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:90405104-90405604 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:90405605-90406105 Neighboring gene NANOG hESC enhancer GRCh37_chr6:90430881-90431382 Neighboring gene DnaJ heat shock protein family (Hsp40) member C19 pseudogene 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    EBI GWAS Catalog

    Description
    Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels.
    EBI GWAS Catalog
    Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study.
    EBI GWAS Catalog

    HIV-1 interactions

    Replication interactions

    Interaction Pubs
    Knockdown of ankyrin repeat domain 6 (ANKRD6) by siRNA inhibits HIV-1 replication in HeLa-derived TZM-bl cells PubMed

    Go to the HIV-1, Human Interaction Database

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ12637, FLJ34916

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables chloroplast targeting sequence binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of canonical Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of JNK cascade IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of Wnt signaling pathway, planar cell polarity pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein targeting to chloroplast IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle IDA
    Inferred from Direct Assay
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    ankyrin repeat domain-containing protein 6
    Names
    diego homolog
    diversin
    epididymis secretory sperm binding protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001242809.2NP_001229738.1  ankyrin repeat domain-containing protein 6 isoform a

      See identical proteins and their annotated locations for NP_001229738.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) and variant 2 encode the same longest isoform (a).
      Source sequence(s)
      AK295731, AL096678, AL138717, DN999929
      Consensus CDS
      CCDS56441.1
      UniProtKB/Swiss-Prot
      B3KUC3, Q5JUJ4, Q5JUJ5, Q8IUQ8, Q9NU24, Q9UFQ9, Q9Y2G4
      UniProtKB/TrEMBL
      B7Z3D2
      Related
      ENSP00000345767.4, ENST00000339746.9
      Conserved Domains (3) summary
      PHA03095
      Location:29265
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:141171
      ANK; ANK repeat [structural motif]
      NF033885
      Location:632724
      conj_TraP_IncI1; conjugal transfer protein TraP
    2. NM_001242811.1NP_001229740.1  ankyrin repeat domain-containing protein 6 isoform a

      See identical proteins and their annotated locations for NP_001229740.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has an alternate 5' UTR exon, and encodes the same isoform a, compared to variant 1.
      Source sequence(s)
      AK295731, AL096678, BC042173, DC317010
      Consensus CDS
      CCDS56441.1
      UniProtKB/Swiss-Prot
      B3KUC3, Q5JUJ4, Q5JUJ5, Q8IUQ8, Q9NU24, Q9UFQ9, Q9Y2G4
      UniProtKB/TrEMBL
      B7Z3D2
      Related
      ENSP00000430985.1, ENST00000522441.5
      Conserved Domains (3) summary
      PHA03095
      Location:29265
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:141171
      ANK; ANK repeat [structural motif]
      NF033885
      Location:632724
      conj_TraP_IncI1; conjugal transfer protein TraP
    3. NM_001242813.1NP_001229742.1  ankyrin repeat domain-containing protein 6 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an in-frame exon in the coding region, compared to variant 1. The resulting isoform (c) lacks an internal segment, compared to isoform a.
      Source sequence(s)
      AB023174, AK295731, AL096678, DN999929
      Consensus CDS
      CCDS56442.1
      UniProtKB/TrEMBL
      B7Z3D2
      Related
      ENSP00000358416.5, ENST00000369408.9
      Conserved Domains (3) summary
      cd00204
      Location:102227
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:141171
      ANK; ANK repeat [structural motif]
      cl26072
      Location:190270
      Ank_5; Ankyrin repeats (many copies)
    4. NM_001242814.1NP_001229743.1  ankyrin repeat domain-containing protein 6 isoform d

      See identical proteins and their annotated locations for NP_001229743.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) lacks two in-frame exons in the coding region, compared to variant 1. The resulting isoform (d) lacks two internal segments, compared to isoform a.
      Source sequence(s)
      AB023174, AK096867, AL096678
      Consensus CDS
      CCDS56443.1
      UniProtKB/TrEMBL
      B7Z3D2
      Related
      ENSP00000429782.1, ENST00000520793.5
      Conserved Domains (5) summary
      cd00204
      Location:37161
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam00023
      Location:174205
      Ank; Ankyrin repeat
      pfam12796
      Location:112204
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:1462
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:108138
      ANK; ANK repeat [structural motif]
    5. NM_014942.4NP_055757.3  ankyrin repeat domain-containing protein 6 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) has an alternate splice site in the coding region, and the open reading frame is retained, compared to variant 1. The resulting isoform (b) lacks an internal segment, compared to isoform a.
      Source sequence(s)
      AK295731, AL096678, BC042173, DN999929
      Consensus CDS
      CCDS47460.1
      UniProtKB/TrEMBL
      B7Z3D2
      Related
      ENSP00000396771.2, ENST00000447838.6
      Conserved Domains (3) summary
      cd00204
      Location:102227
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:141171
      ANK; ANK repeat [structural motif]
      cl26073
      Location:127382
      Ank_2; Ankyrin repeats (3 copies)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

      Range
      89433152..89633834
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047418408.1XP_047274364.1  ankyrin repeat domain-containing protein 6 isoform X34

    2. XM_047418410.1XP_047274366.1  ankyrin repeat domain-containing protein 6 isoform X34

    3. XM_047418412.1XP_047274368.1  ankyrin repeat domain-containing protein 6 isoform X34

    4. XM_047418413.1XP_047274369.1  ankyrin repeat domain-containing protein 6 isoform X34

    5. XM_047418415.1XP_047274371.1  ankyrin repeat domain-containing protein 6 isoform X34

    6. XM_005248681.3XP_005248738.1  ankyrin repeat domain-containing protein 6 isoform X38

      See identical proteins and their annotated locations for XP_005248738.1

      UniProtKB/Swiss-Prot
      B3KUC3, Q5JUJ4, Q5JUJ5, Q8IUQ8, Q9NU24, Q9UFQ9, Q9Y2G4
      UniProtKB/TrEMBL
      B7Z3D2
      Conserved Domains (3) summary
      PHA03095
      Location:29265
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:141171
      ANK; ANK repeat [structural motif]
      NF033885
      Location:632724
      conj_TraP_IncI1; conjugal transfer protein TraP
    7. XM_047418398.1XP_047274354.1  ankyrin repeat domain-containing protein 6 isoform X4

    8. XM_047418401.1XP_047274357.1  ankyrin repeat domain-containing protein 6 isoform X11

    9. XM_047418405.1XP_047274361.1  ankyrin repeat domain-containing protein 6 isoform X21

    10. XM_017010513.2XP_016866002.1  ankyrin repeat domain-containing protein 6 isoform X33

      Conserved Domains (3) summary
      cd00204
      Location:14128
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
      cl26073
      Location:42222
      Ank_2; Ankyrin repeats (3 copies)
    11. XM_047418409.1XP_047274365.1  ankyrin repeat domain-containing protein 6 isoform X35

    12. XM_047418402.1XP_047274358.1  ankyrin repeat domain-containing protein 6 isoform X13

    13. XM_024446357.2XP_024302125.1  ankyrin repeat domain-containing protein 6 isoform X4

      UniProtKB/TrEMBL
      B7Z3D2
      Conserved Domains (3) summary
      cd00204
      Location:102227
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:141171
      ANK; ANK repeat [structural motif]
      cl26073
      Location:127382
      Ank_2; Ankyrin repeats (3 copies)
    14. XM_024446359.2XP_024302127.1  ankyrin repeat domain-containing protein 6 isoform X14

      UniProtKB/TrEMBL
      B7Z3D2
      Conserved Domains (3) summary
      cd00204
      Location:102227
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:141171
      ANK; ANK repeat [structural motif]
      cl26072
      Location:190270
      Ank_5; Ankyrin repeats (many copies)
    15. XM_024446361.2XP_024302129.1  ankyrin repeat domain-containing protein 6 isoform X16

      UniProtKB/TrEMBL
      B7Z3D2
      Conserved Domains (3) summary
      cd00204
      Location:102227
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:141171
      ANK; ANK repeat [structural motif]
      cl26072
      Location:190270
      Ank_5; Ankyrin repeats (many copies)
    16. XM_047418399.1XP_047274355.1  ankyrin repeat domain-containing protein 6 isoform X9

    17. XM_047418400.1XP_047274356.1  ankyrin repeat domain-containing protein 6 isoform X10

    18. XM_024446358.2XP_024302126.1  ankyrin repeat domain-containing protein 6 isoform X11

      UniProtKB/TrEMBL
      B7Z3D2
      Conserved Domains (2) summary
      cd00204
      Location:37161
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
    19. XM_024446360.2XP_024302128.1  ankyrin repeat domain-containing protein 6 isoform X15

      UniProtKB/TrEMBL
      B7Z3D2
      Conserved Domains (2) summary
      cd00204
      Location:37161
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
    20. XM_024446363.2XP_024302131.1  ankyrin repeat domain-containing protein 6 isoform X24

      UniProtKB/TrEMBL
      B7Z3D2
      Conserved Domains (2) summary
      cd00204
      Location:37161
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
    21. XM_024446362.2XP_024302130.1  ankyrin repeat domain-containing protein 6 isoform X21

      UniProtKB/TrEMBL
      B7Z3D2
      Conserved Domains (3) summary
      cd00204
      Location:37161
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:141193
      Ank_4; Ankyrin repeats (many copies)
    22. XM_024446364.2XP_024302132.1  ankyrin repeat domain-containing protein 6 isoform X25

      UniProtKB/TrEMBL
      B7Z3D2
      Conserved Domains (3) summary
      cd00204
      Location:37161
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:141193
      Ank_4; Ankyrin repeats (many copies)
    23. XM_024446366.2XP_024302134.1  ankyrin repeat domain-containing protein 6 isoform X30

      UniProtKB/TrEMBL
      B7Z3D2
      Conserved Domains (3) summary
      cd00204
      Location:37161
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:141193
      Ank_4; Ankyrin repeats (many copies)
    24. XM_047418407.1XP_047274363.1  ankyrin repeat domain-containing protein 6 isoform X28

    25. XM_024446368.2XP_024302136.1  ankyrin repeat domain-containing protein 6 isoform X33

      Conserved Domains (3) summary
      cd00204
      Location:14128
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
      cl26073
      Location:42222
      Ank_2; Ankyrin repeats (3 copies)
    26. XM_047418404.1XP_047274360.1  ankyrin repeat domain-containing protein 6 isoform X20

    27. XM_024446365.2XP_024302133.1  ankyrin repeat domain-containing protein 6 isoform X26

      UniProtKB/TrEMBL
      B7Z3D2
      Conserved Domains (3) summary
      cd00204
      Location:37161
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:141193
      Ank_4; Ankyrin repeats (many copies)
    28. XM_017010496.3XP_016865985.1  ankyrin repeat domain-containing protein 6 isoform X12

      UniProtKB/TrEMBL
      B7Z3D2
      Conserved Domains (4) summary
      cd00204
      Location:69194
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:112204
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:1462
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:108138
      ANK; ANK repeat [structural motif]
    29. XM_017010502.3XP_016865991.1  ankyrin repeat domain-containing protein 6 isoform X22

      UniProtKB/TrEMBL
      B7Z3D2
    30. XM_017010508.2XP_016865997.1  ankyrin repeat domain-containing protein 6 isoform X29

      UniProtKB/TrEMBL
      B7Z3D2
    31. XM_017010511.3XP_016866000.1  ankyrin repeat domain-containing protein 6 isoform X31

      UniProtKB/TrEMBL
      B7Z3D2
    32. XM_047418411.1XP_047274367.1  ankyrin repeat domain-containing protein 6 isoform X36

    33. XM_017010503.2XP_016865992.1  ankyrin repeat domain-containing protein 6 isoform X23

      UniProtKB/TrEMBL
      B7Z3D2
    34. XM_005248679.4XP_005248736.1  ankyrin repeat domain-containing protein 6 isoform X1

      UniProtKB/TrEMBL
      A0AA34QVS0
      Related
      ENSP00000518190.1, ENST00000710308.1
      Conserved Domains (3) summary
      cd00204
      Location:127252
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:170262
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:166196
      ANK; ANK repeat [structural motif]
    35. XM_047418397.1XP_047274353.1  ankyrin repeat domain-containing protein 6 isoform X2

    36. XM_017010493.2XP_016865982.1  ankyrin repeat domain-containing protein 6 isoform X7

    37. XM_005248682.4XP_005248739.1  ankyrin repeat domain-containing protein 6 isoform X3

      Conserved Domains (3) summary
      cd00204
      Location:127252
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:170262
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:166196
      ANK; ANK repeat [structural motif]
    38. XM_011535596.3XP_011533898.1  ankyrin repeat domain-containing protein 6 isoform X5

      Conserved Domains (4) summary
      cd00204
      Location:127251
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:137229
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:102153
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:132163
      ANK; ANK repeat [structural motif]
    39. XM_017010494.2XP_016865983.1  ankyrin repeat domain-containing protein 6 isoform X8

    40. XM_017010499.2XP_016865988.1  ankyrin repeat domain-containing protein 6 isoform X18

    41. XM_005248683.4XP_005248740.1  ankyrin repeat domain-containing protein 6 isoform X17

      Conserved Domains (3) summary
      cd00204
      Location:101218
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:104196
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:101130
      ANK; ANK repeat [structural motif]
    42. XM_017010500.2XP_016865989.1  ankyrin repeat domain-containing protein 6 isoform X19

    43. XM_005248684.4XP_005248741.1  ankyrin repeat domain-containing protein 6 isoform X32

      Conserved Domains (3) summary
      cd00204
      Location:101173
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam13637
      Location:102153
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:98130
      ANK; ANK repeat [structural motif]
    44. XM_011535597.3XP_011533899.1  ankyrin repeat domain-containing protein 6 isoform X6

      Conserved Domains (4) summary
      cd00204
      Location:127251
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:137229
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:102153
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:133163
      ANK; ANK repeat [structural motif]
    45. XM_047418406.1XP_047274362.1  ankyrin repeat domain-containing protein 6 isoform X27

    46. XM_047418414.1XP_047274370.1  ankyrin repeat domain-containing protein 6 isoform X37

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060930.1 Alternate T2T-CHM13v2.0

      Range
      90642513..90843208
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054354721.1XP_054210696.1  ankyrin repeat domain-containing protein 6 isoform X34

    2. XM_054354723.1XP_054210698.1  ankyrin repeat domain-containing protein 6 isoform X34

    3. XM_054354725.1XP_054210700.1  ankyrin repeat domain-containing protein 6 isoform X34

    4. XM_054354726.1XP_054210701.1  ankyrin repeat domain-containing protein 6 isoform X34

    5. XM_054354728.1XP_054210703.1  ankyrin repeat domain-containing protein 6 isoform X34

    6. XM_054354691.1XP_054210666.1  ankyrin repeat domain-containing protein 6 isoform X4

      UniProtKB/TrEMBL
      A0A384MEC3
    7. XM_054354701.1XP_054210676.1  ankyrin repeat domain-containing protein 6 isoform X14

    8. XM_054354703.1XP_054210678.1  ankyrin repeat domain-containing protein 6 isoform X16

    9. XM_054354696.1XP_054210671.1  ankyrin repeat domain-containing protein 6 isoform X9

    10. XM_054354697.1XP_054210672.1  ankyrin repeat domain-containing protein 6 isoform X10

    11. XM_054354698.1XP_054210673.1  ankyrin repeat domain-containing protein 6 isoform X11

    12. XM_054354702.1XP_054210677.1  ankyrin repeat domain-containing protein 6 isoform X15

    13. XM_054354711.1XP_054210686.1  ankyrin repeat domain-containing protein 6 isoform X24

    14. XM_054354708.1XP_054210683.1  ankyrin repeat domain-containing protein 6 isoform X21

    15. XM_054354712.1XP_054210687.1  ankyrin repeat domain-containing protein 6 isoform X25

    16. XM_054354717.1XP_054210692.1  ankyrin repeat domain-containing protein 6 isoform X30

    17. XM_054354715.1XP_054210690.1  ankyrin repeat domain-containing protein 6 isoform X28

    18. XM_054354720.1XP_054210695.1  ankyrin repeat domain-containing protein 6 isoform X33

    19. XM_054354707.1XP_054210682.1  ankyrin repeat domain-containing protein 6 isoform X20

    20. XM_054354713.1XP_054210688.1  ankyrin repeat domain-containing protein 6 isoform X26

    21. XM_054354699.1XP_054210674.1  ankyrin repeat domain-containing protein 6 isoform X12

    22. XM_054354709.1XP_054210684.1  ankyrin repeat domain-containing protein 6 isoform X22

    23. XM_054354716.1XP_054210691.1  ankyrin repeat domain-containing protein 6 isoform X29

    24. XM_054354718.1XP_054210693.1  ankyrin repeat domain-containing protein 6 isoform X31

    25. XM_054354724.1XP_054210699.1  ankyrin repeat domain-containing protein 6 isoform X36

    26. XM_054354710.1XP_054210685.1  ankyrin repeat domain-containing protein 6 isoform X23

    27. XM_054354722.1XP_054210697.1  ankyrin repeat domain-containing protein 6 isoform X35

    28. XM_054354700.1XP_054210675.1  ankyrin repeat domain-containing protein 6 isoform X13

    29. XM_054354688.1XP_054210663.1  ankyrin repeat domain-containing protein 6 isoform X1

    30. XM_054354689.1XP_054210664.1  ankyrin repeat domain-containing protein 6 isoform X2

    31. XM_054354694.1XP_054210669.1  ankyrin repeat domain-containing protein 6 isoform X7

    32. XM_054354690.1XP_054210665.1  ankyrin repeat domain-containing protein 6 isoform X3

    33. XM_054354692.1XP_054210667.1  ankyrin repeat domain-containing protein 6 isoform X5

    34. XM_054354695.1XP_054210670.1  ankyrin repeat domain-containing protein 6 isoform X8

    35. XM_054354705.1XP_054210680.1  ankyrin repeat domain-containing protein 6 isoform X18

    36. XM_054354704.1XP_054210679.1  ankyrin repeat domain-containing protein 6 isoform X17

    37. XM_054354706.1XP_054210681.1  ankyrin repeat domain-containing protein 6 isoform X19

    38. XM_054354719.1XP_054210694.1  ankyrin repeat domain-containing protein 6 isoform X32

    39. XM_054354693.1XP_054210668.1  ankyrin repeat domain-containing protein 6 isoform X6

    40. XM_054354714.1XP_054210689.1  ankyrin repeat domain-containing protein 6 isoform X27

    41. XM_054354727.1XP_054210702.1  ankyrin repeat domain-containing protein 6 isoform X37