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    FGGY FGGY carbohydrate kinase domain containing [ Homo sapiens (human) ]

    Gene ID: 55277, updated on 9-Dec-2024

    Summary

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    Official Symbol
    FGGYprovided by HGNC
    Official Full Name
    FGGY carbohydrate kinase domain containingprovided by HGNC
    Primary source
    HGNC:HGNC:25610
    See related
    Ensembl:ENSG00000172456 MIM:611370; AllianceGenome:HGNC:25610
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This gene encodes a protein that phosphorylates carbohydrates such as ribulose, ribitol, and L-arabinitol. Genome-wide association studies in some populations have found an association between polymorphisms in this gene and sporadic amyotrophic lateral sclerosis, but studies of other populations have not been able to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
    Expression
    Ubiquitous expression in liver (RPKM 2.1), kidney (RPKM 1.3) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See FGGY in Genome Data Viewer
    Location:
    1p32.1
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (59296378..59762730)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (59174750..59641176)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (59762485..60228402)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1104 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1105 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1106 Neighboring gene VISTA enhancer hs1485 Neighboring gene long intergenic non-protein coding RNA 1358 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:59542215-59542758 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:59543303-59543846 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr1:59543847-59544388 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:59572908-59573408 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:59573409-59573909 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:59604949-59605450 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:59605451-59605950 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1107 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 939 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:59672311-59672933 Neighboring gene uncharacterized LOC729467 Neighboring gene Sharpr-MPRA regulatory region 10857 Neighboring gene Sharpr-MPRA regulatory region 13133 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1108 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1109 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 940 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 941 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:59764225-59765424 Neighboring gene FGGY divergent transcript Neighboring gene MPRA-validated peak254 silencer Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_8792 Neighboring gene MPRA-validated peak255 silencer Neighboring gene uncharacterized LOC124904192 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1110 Neighboring gene MPRA-validated peak256 silencer Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:60134970-60135524 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:60139185-60139712 Neighboring gene Sharpr-MPRA regulatory region 6224 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 942 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1111 Neighboring gene uncharacterized LOC105378758 Neighboring gene uncharacterized LOC101926944 Neighboring gene microRNA 4711 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 943 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr1:60280925-60281488 Neighboring gene hook microtubule tethering protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. LINE-1 Retrotransposition Promotes the Development and Progression of Lung Squamous Cell Carcinoma by Disrupting the Tumor-Suppressor Gene FGGY. Zhang R, et al. Cancer Res, 2019 Sep 1. PMID 31289132
    2. Clinical and genetic features of patients with sporadic amyotrophic lateral sclerosis in south-west China. Fang DF, et al. Amyotroph Lateral Scler, 2009 Oct-Dec. PMID 19922123
    3. Analysis of FGGY as a risk factor for sporadic amyotrophic lateral sclerosis. Van Es MA, et al. Amyotroph Lateral Scler, 2009 Oct-Dec. PMID 19922138
    4. Single-nucleotide polymorphism rs6690993 in FGGY is not associated with amyotrophic lateral sclerosisin a large Chinese cohort. Cai B, et al. Neurobiol Aging, 2014 Jun. PMID 24439956
    5. Whole-genome analysis of sporadic amyotrophic lateral sclerosis. Dunckley T, et al. N Engl J Med, 2007 Aug 23. PMID 17671248

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LINE-1-FGGY expression corresponded with smoke-induced LINE-1 promoter hypomethylation, lipid metabolism dysregulation, and immune microenvironment alteration in the lung squamous cell carcinoma.
      Title: LINE-1 Retrotransposition Promotes the Development and Progression of Lung Squamous Cell Carcinoma by Disrupting the Tumor-Suppressor Gene FGGY.
    2. S. cerevisiae Ydr109c and human FGGY could act as metabolite repair enzymes, serving to re-phosphorylate free d-ribulose generated by promiscuous phosphatases from d-ribulose 5-phosphate. In human cells, FGGY can additionally participate in ribitol metabolism.
      Title: Molecular Identification of d-Ribulokinase in Budding Yeast and Mammals.
    3. Single-nucleotide polymorphism in FGGY is not associated with amyotrophic lateral sclerosis in a large Chinese cohort.
      Title: Single-nucleotide polymorphism rs6690993 in FGGY is not associated with amyotrophic lateral sclerosisin a large Chinese cohort.
    4. The result of this study suggested that FLJI0986 that do not modulate the risk for SALS in the German population.
      Title: No evidence of association of FLJ10986 and ITPR2 with ALS in a large German cohort.
    5. This study indicated that mutations in fggy genes are unlikely to be a common cause of ALS in the French and French Canadian populations.
      Title: Analysis of DPP6 and FGGY as candidate genes for amyotrophic lateral sclerosis.
    6. Results suggest that common genetic variation in FGGY is not associated with susceptibility to sporadic ALS in genetically homogeneous populations from northern Europe.
      Title: Analysis of FGGY as a risk factor for sporadic amyotrophic lateral sclerosis.
    7. Observational study of gene-disease association. (HuGE Navigator)
      Title: Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.
    8. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
      Title: A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis.
    9. Genome-wide association study of gene-disease association. (HuGE Navigator)
      Title: Whole-genome analysis of sporadic amyotrophic lateral sclerosis.
    10. Variants of FLJ10986 may confer susceptibility to sporadic ALS (amyotrophic lateral sclerosis).
      Title: Whole-genome analysis of sporadic amyotrophic lateral sclerosis.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women.
    EBI GWAS Catalog
    Genomewide association study of movement-related adverse antipsychotic effects.
    EBI GWAS Catalog
    Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ10986

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables D-ribulokinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in neuron cellular homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in pentose metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    FGGY carbohydrate kinase domain-containing protein
    Names
    D-ribulokinase
    D-ribulokinase FGGY
    NP_001106882.1
    NP_001231643.1
    NP_001265153.1
    NP_001337719.1
    NP_001337720.1
    NP_001337721.1
    NP_001337722.1
    NP_001337723.1
    NP_001337724.1
    NP_001337725.1
    NP_001337726.1
    NP_001337727.1
    NP_001337728.1
    NP_060761.3
    XP_011540032.1
    XP_011540033.1
    XP_011540038.1
    XP_016857132.1
    XP_016857134.1
    XP_016857135.1
    XP_016857138.1
    XP_016857141.1
    XP_016857144.1
    XP_016857151.1
    XP_016857153.1
    XP_016857157.1
    XP_016857158.1
    XP_016857159.1
    XP_016857160.1
    XP_016857166.1
    XP_016857167.1
    XP_016857168.1
    XP_024303944.1
    XP_024303997.1
    XP_047280336.1
    XP_047280337.1
    XP_047280338.1
    XP_047280339.1
    XP_047280340.1
    XP_047280341.1
    XP_047280342.1
    XP_047280343.1
    XP_047280344.1
    XP_047280345.1
    XP_047280346.1
    XP_047280347.1
    XP_047280348.1
    XP_047280349.1
    XP_047280350.1
    XP_047280351.1
    XP_047280352.1
    XP_047280353.1
    XP_047280354.1
    XP_047280355.1
    XP_047280356.1
    XP_047280357.1
    XP_054193428.1
    XP_054193429.1
    XP_054193430.1
    XP_054193431.1
    XP_054193432.1
    XP_054193433.1
    XP_054193434.1
    XP_054193435.1
    XP_054193436.1
    XP_054193437.1
    XP_054193438.1
    XP_054193439.1
    XP_054193440.1
    XP_054193441.1
    XP_054193442.1
    XP_054193443.1
    XP_054193444.1
    XP_054193445.1
    XP_054193446.1
    XP_054193447.1
    XP_054193448.1
    XP_054193449.1
    XP_054193450.1
    XP_054193451.1
    XP_054193452.1
    XP_054193453.1
    XP_054193454.1
    XP_054193455.1
    XP_054193456.1
    XP_054193457.1
    XP_054193458.1
    XP_054193459.1
    XP_054193460.1
    XP_054193461.1
    XP_054193462.1
    XP_054193463.1
    XP_054193464.1
    XP_054193465.1
    XP_054193466.1
    XP_054193467.1
    XP_054193468.1
    XP_054193469.1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_030039.1 RefSeqGene

      Range
      5142..470778
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001113411.2 → NP_001106882.1  FGGY carbohydrate kinase domain-containing protein isoform a

      See identical proteins and their annotated locations for NP_001106882.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (a). Variants 1 and 6 encode the same protein (isoform a).
      Source sequence(s)
      AA830864, BC014947, BX647626
      Consensus CDS
      CCDS44155.1
      UniProtKB/TrEMBL
      F2Z2V1
      Related
      ENSP00000360262.4, ENST00000371218.8
      Conserved Domains (1) summary
      cd07782
      Location:10 → 568
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    2. NM_001244714.2 → NP_001231643.1  FGGY carbohydrate kinase domain-containing protein isoform c

      See identical proteins and their annotated locations for NP_001231643.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and lacks three alternate in-frame exons, compared to variant 1. The encoded isoform (c) is shorter than isoform a.
      Source sequence(s)
      AC093424, AK054842, BU630162, DA072156
      Consensus CDS
      CCDS58003.1
      UniProtKB/TrEMBL
      F2Z2V1
      Related
      ENSP00000360256.1, ENST00000371212.5
      Conserved Domains (2) summary
      cd07782
      Location:10 → 456
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases
      TIGR01315
      Location:11 → 456
      5C_CHO_kinase; FGGY-family pentulose kinase

    3. NM_001278224.2 → NP_001265153.1  FGGY carbohydrate kinase domain-containing protein isoform d

      See identical proteins and their annotated locations for NP_001265153.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR and contains multiple differences in the coding region, including the lack of multiple 5' coding exons, compared to variant 1. It represents use of an alternate promoter and initiates translation at a downstream in-frame start codon. The encoded isoform (d) has a shorter N-terminus, compared to isoform a.
      Source sequence(s)
      AL390234, BC014947
      Consensus CDS
      CCDS60155.1
      UniProtKB/Swiss-Prot
      Q96C11
      Related
      ENSP00000360254.1, ENST00000371210.1
      Conserved Domains (1) summary
      cl17037
      Location:1 → 245
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    4. NM_001350790.2 → NP_001337719.1  FGGY carbohydrate kinase domain-containing protein isoform a

      Status: REVIEWED

      Source sequence(s)
      AA830864, AC093424, AK054842, BC014947, BX647626, DA072156
      Consensus CDS
      CCDS44155.1
      UniProtKB/TrEMBL
      F2Z2V1
      Conserved Domains (1) summary
      cd07782
      Location:10 → 568
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    5. NM_001350791.2 → NP_001337720.1  FGGY carbohydrate kinase domain-containing protein isoform b

      Status: REVIEWED

      Source sequence(s)
      AC093424, AK054842, BC014947, DA072156
      Consensus CDS
      CCDS611.2
      UniProtKB/Swiss-Prot
      B1AK92, B1AK93, B1AK94, B2RDR8, D3DQ56, Q96C11, Q9HA63, Q9NV20
      UniProtKB/TrEMBL
      F2Z2V1
      Conserved Domains (1) summary
      cd07782
      Location:10 → 544
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    6. NM_001350792.2 → NP_001337721.1  FGGY carbohydrate kinase domain-containing protein isoform e

      Status: REVIEWED

      Source sequence(s)
      AC093424, AK054842, BI260394, BU630162, DA072156
      UniProtKB/TrEMBL
      F2Z2V1
      Conserved Domains (1) summary
      cd07782
      Location:12 → 488
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    7. NM_001350793.2 → NP_001337722.1  FGGY carbohydrate kinase domain-containing protein isoform e

      Status: REVIEWED

      Source sequence(s)
      AC093424, AK054842, BI260394, BU630162, DA270957
      UniProtKB/TrEMBL
      F2Z2V1
      Conserved Domains (1) summary
      cd07782
      Location:12 → 488
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    8. NM_001350794.2 → NP_001337723.1  FGGY carbohydrate kinase domain-containing protein isoform f

      Status: REVIEWED

      Source sequence(s)
      AC093424, AK054842, BM688624, BU630162, CA425949, DA072156, DN990967
      UniProtKB/TrEMBL
      F2Z2V1
      Conserved Domains (1) summary
      cd07782
      Location:10 → 473
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    9. NM_001350795.2 → NP_001337724.1  FGGY carbohydrate kinase domain-containing protein isoform g

      Status: REVIEWED

      Source sequence(s)
      AA830864, BC014947, BX647626
      UniProtKB/TrEMBL
      F2Z2V1
      Conserved Domains (1) summary
      cd07782
      Location:10 → 480
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    10. NM_001350796.2 → NP_001337725.1  FGGY carbohydrate kinase domain-containing protein isoform h

      Status: REVIEWED

      Source sequence(s)
      AK054842, BU630162, DA270957
      Conserved Domains (1) summary
      cd07782
      Location:1 → 432
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    11. NM_001350797.2 → NP_001337726.1  FGGY carbohydrate kinase domain-containing protein isoform i

      Status: REVIEWED

      Source sequence(s)
      AC093424, AK054842, BI260394, BU630162, DA270957
      Conserved Domains (1) summary
      cd07782
      Location:1 → 410
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    12. NM_001350798.2 → NP_001337727.1  FGGY carbohydrate kinase domain-containing protein isoform j

      Status: REVIEWED

      Source sequence(s)
      AK054842, BU630162, BX647626, DA270957
      Conserved Domains (1) summary
      cd07782
      Location:1 → 385
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    13. NM_001350799.2 → NP_001337728.1  FGGY carbohydrate kinase domain-containing protein isoform k

      Status: REVIEWED

      Source sequence(s)
      AC093424, AK054842, BM688624, BU630162, DA072156, DA270957
      Conserved Domains (1) summary
      cd07782
      Location:1 → 361
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    14. NM_018291.5 → NP_060761.3  FGGY carbohydrate kinase domain-containing protein isoform b

      See identical proteins and their annotated locations for NP_060761.3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1. The encoded isoform (b) is shorter than isoform a. Variants 2 and 7 encode the same protein (isoform b).
      Source sequence(s)
      AL035416, BC014947
      Consensus CDS
      CCDS611.2
      UniProtKB/Swiss-Prot
      B1AK92, B1AK93, B1AK94, B2RDR8, D3DQ56, Q96C11, Q9HA63, Q9NV20
      UniProtKB/TrEMBL
      F2Z2V1
      Related
      ENSP00000305922.8, ENST00000303721.12
      Conserved Domains (1) summary
      cd07782
      Location:10 → 544
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    RNA

    1. NR_103473.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) contains multiple differences at the 5' and 3' ends, compared to variant 1. This variant is represented as non-coding because use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AK090568, BC014947
      Related
      ENST00000430447.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      59296378..59762730
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011541731.2 → XP_011540033.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      See identical proteins and their annotated locations for XP_011540033.1

      UniProtKB/TrEMBL
      F2Z2V1
      Conserved Domains (1) summary
      cd07782
      Location:10 → 568
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    2. XM_047424383.1 → XP_047280339.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F2Z2V1

    3. XM_011541730.2 → XP_011540032.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      See identical proteins and their annotated locations for XP_011540032.1

      UniProtKB/TrEMBL
      F2Z2V1
      Conserved Domains (1) summary
      cd07782
      Location:10 → 568
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    4. XM_017001645.2 → XP_016857134.1  FGGY carbohydrate kinase domain-containing protein isoform X2

      UniProtKB/Swiss-Prot
      B1AK92, B1AK93, B1AK94, B2RDR8, D3DQ56, Q96C11, Q9HA63, Q9NV20
      UniProtKB/TrEMBL
      F2Z2V1
      Conserved Domains (1) summary
      cd07782
      Location:10 → 544
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    5. XM_017001655.2 → XP_016857144.1  FGGY carbohydrate kinase domain-containing protein isoform X6

      UniProtKB/TrEMBL
      F2Z2V1
      Conserved Domains (1) summary
      cd07782
      Location:10 → 480
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    6. XM_017001671.2 → XP_016857160.1  FGGY carbohydrate kinase domain-containing protein isoform X9

    7. XM_047424393.1 → XP_047280349.1  FGGY carbohydrate kinase domain-containing protein isoform X8

    8. XM_047424387.1 → XP_047280343.1  FGGY carbohydrate kinase domain-containing protein isoform X2

      UniProtKB/Swiss-Prot
      B1AK92, B1AK93, B1AK94, B2RDR8, D3DQ56, Q96C11, Q9HA63, Q9NV20
      UniProtKB/TrEMBL
      F2Z2V1
      Related
      ENSP00000489446.1, ENST00000634364.1

    9. XM_024448176.2 → XP_024303944.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F2Z2V1
      Conserved Domains (1) summary
      cd07782
      Location:10 → 568
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    10. XM_047424386.1 → XP_047280342.1  FGGY carbohydrate kinase domain-containing protein isoform X2

      UniProtKB/Swiss-Prot
      B1AK92, B1AK93, B1AK94, B2RDR8, D3DQ56, Q96C11, Q9HA63, Q9NV20
      UniProtKB/TrEMBL
      F2Z2V1

    11. XM_047424380.1 → XP_047280336.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F2Z2V1

    12. XM_017001649.2 → XP_016857138.1  FGGY carbohydrate kinase domain-containing protein isoform X4

      UniProtKB/TrEMBL
      F2Z2V1
      Conserved Domains (1) summary
      cd07782
      Location:10 → 497
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    13. XM_017001652.2 → XP_016857141.1  FGGY carbohydrate kinase domain-containing protein isoform X5

      UniProtKB/TrEMBL
      F2Z2V1
      Conserved Domains (1) summary
      cd07782
      Location:10 → 473
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    14. XM_047424390.1 → XP_047280346.1  FGGY carbohydrate kinase domain-containing protein isoform X7

      UniProtKB/TrEMBL
      F2Z2V1

    15. XM_017001669.3 → XP_016857158.1  FGGY carbohydrate kinase domain-containing protein isoform X9

    16. XM_017001664.3 → XP_016857153.1  FGGY carbohydrate kinase domain-containing protein isoform X8

      Conserved Domains (1) summary
      cd07782
      Location:1 → 456
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    17. XM_017001679.2 → XP_016857168.1  FGGY carbohydrate kinase domain-containing protein isoform X12

      Conserved Domains (1) summary
      cd07782
      Location:10 → 358
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    18. XM_047424382.1 → XP_047280338.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F2Z2V1

    19. XM_047424388.1 → XP_047280344.1  FGGY carbohydrate kinase domain-containing protein isoform X2

      UniProtKB/Swiss-Prot
      B1AK92, B1AK93, B1AK94, B2RDR8, D3DQ56, Q96C11, Q9HA63, Q9NV20
      UniProtKB/TrEMBL
      F2Z2V1

    20. XM_047424385.1 → XP_047280341.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F2Z2V1

    21. XM_017001643.3 → XP_016857132.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F2Z2V1
      Conserved Domains (1) summary
      cd07782
      Location:10 → 568
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    22. XM_047424391.1 → XP_047280347.1  FGGY carbohydrate kinase domain-containing protein isoform X7

      UniProtKB/TrEMBL
      F2Z2V1

    23. XM_047424384.1 → XP_047280340.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F2Z2V1

    24. XM_017001646.2 → XP_016857135.1  FGGY carbohydrate kinase domain-containing protein isoform X2

      UniProtKB/Swiss-Prot
      B1AK92, B1AK93, B1AK94, B2RDR8, D3DQ56, Q96C11, Q9HA63, Q9NV20
      UniProtKB/TrEMBL
      F2Z2V1
      Conserved Domains (1) summary
      cd07782
      Location:10 → 544
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    25. XM_011541736.4 → XP_011540038.1  FGGY carbohydrate kinase domain-containing protein isoform X6

      See identical proteins and their annotated locations for XP_011540038.1

      UniProtKB/TrEMBL
      F2Z2V1
      Conserved Domains (1) summary
      cd07782
      Location:10 → 480
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    26. XM_047424381.1 → XP_047280337.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F2Z2V1

    27. XM_017001668.1 → XP_016857157.1  FGGY carbohydrate kinase domain-containing protein isoform X9

    28. XM_047424389.1 → XP_047280345.1  FGGY carbohydrate kinase domain-containing protein isoform X3

      UniProtKB/TrEMBL
      F2Z2V1

    29. XM_047424396.1 → XP_047280352.1  FGGY carbohydrate kinase domain-containing protein isoform X9

    30. XM_047424397.1 → XP_047280353.1  FGGY carbohydrate kinase domain-containing protein isoform X9

    31. XM_047424395.1 → XP_047280351.1  FGGY carbohydrate kinase domain-containing protein isoform X9

    32. XM_047424392.1 → XP_047280348.1  FGGY carbohydrate kinase domain-containing protein isoform X8

    33. XM_047424394.1 → XP_047280350.1  FGGY carbohydrate kinase domain-containing protein isoform X9

    34. XM_017001670.3 → XP_016857159.1  FGGY carbohydrate kinase domain-containing protein isoform X9

    35. XM_047424398.1 → XP_047280354.1  FGGY carbohydrate kinase domain-containing protein isoform X10

    36. XM_017001662.3 → XP_016857151.1  FGGY carbohydrate kinase domain-containing protein isoform X8

      Conserved Domains (1) summary
      cd07782
      Location:1 → 456
      FGGY_YpCarbK_like; Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases

    37. XM_047424399.1 → XP_047280355.1  FGGY carbohydrate kinase domain-containing protein isoform X11

    38. XM_017001678.2 → XP_016857167.1  FGGY carbohydrate kinase domain-containing protein isoform X11

      Conserved Domains (1) summary
      cl17037
      Location:2 → 360
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    39. XM_024448229.2 → XP_024303997.1  FGGY carbohydrate kinase domain-containing protein isoform X14

      Conserved Domains (1) summary
      cl17037
      Location:2 → 336
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    40. XM_017001677.2 → XP_016857166.1  FGGY carbohydrate kinase domain-containing protein isoform X11

      Conserved Domains (1) summary
      cl17037
      Location:2 → 360
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    41. XM_047424400.1 → XP_047280356.1  FGGY carbohydrate kinase domain-containing protein isoform X11

    42. XM_047424401.1 → XP_047280357.1  FGGY carbohydrate kinase domain-containing protein isoform X13

    RNA

    1. XR_007061929.1 RNA Sequence

    2. XR_007061930.1 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      59174750..59641176
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054337456.1 → XP_054193431.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F2Z2V1

    2. XM_054337459.1 → XP_054193434.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F2Z2V1

    3. XM_054337454.1 → XP_054193429.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F2Z2V1

    4. XM_054337463.1 → XP_054193438.1  FGGY carbohydrate kinase domain-containing protein isoform X2

      UniProtKB/Swiss-Prot
      B1AK92, B1AK93, B1AK94, B2RDR8, D3DQ56, Q96C11, Q9HA63, Q9NV20
      UniProtKB/TrEMBL
      F2Z2V1

    5. XM_054337471.1 → XP_054193446.1  FGGY carbohydrate kinase domain-containing protein isoform X6

      UniProtKB/TrEMBL
      F2Z2V1

    6. XM_054337485.1 → XP_054193460.1  FGGY carbohydrate kinase domain-containing protein isoform X9

    7. XM_054337478.1 → XP_054193453.1  FGGY carbohydrate kinase domain-containing protein isoform X8

    8. XM_054337466.1 → XP_054193441.1  FGGY carbohydrate kinase domain-containing protein isoform X2

      UniProtKB/Swiss-Prot
      B1AK92, B1AK93, B1AK94, B2RDR8, D3DQ56, Q96C11, Q9HA63, Q9NV20
      UniProtKB/TrEMBL
      F2Z2V1

    9. XM_054337458.1 → XP_054193433.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F2Z2V1

    10. XM_054337464.1 → XP_054193439.1  FGGY carbohydrate kinase domain-containing protein isoform X2

      UniProtKB/Swiss-Prot
      B1AK92, B1AK93, B1AK94, B2RDR8, D3DQ56, Q96C11, Q9HA63, Q9NV20
      UniProtKB/TrEMBL
      F2Z2V1

    11. XM_054337453.1 → XP_054193428.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F2Z2V1

    12. XM_054337469.1 → XP_054193444.1  FGGY carbohydrate kinase domain-containing protein isoform X4

      UniProtKB/TrEMBL
      F2Z2V1

    13. XM_054337470.1 → XP_054193445.1  FGGY carbohydrate kinase domain-containing protein isoform X5

      UniProtKB/TrEMBL
      F2Z2V1

    14. XM_054337473.1 → XP_054193448.1  FGGY carbohydrate kinase domain-containing protein isoform X7

      UniProtKB/TrEMBL
      F2Z2V1

    15. XM_054337483.1 → XP_054193458.1  FGGY carbohydrate kinase domain-containing protein isoform X9

    16. XM_054337477.1 → XP_054193452.1  FGGY carbohydrate kinase domain-containing protein isoform X8

    17. XM_054337492.1 → XP_054193467.1  FGGY carbohydrate kinase domain-containing protein isoform X12

    18. XM_054337457.1 → XP_054193432.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F2Z2V1

    19. XM_054337467.1 → XP_054193442.1  FGGY carbohydrate kinase domain-containing protein isoform X2

      UniProtKB/Swiss-Prot
      B1AK92, B1AK93, B1AK94, B2RDR8, D3DQ56, Q96C11, Q9HA63, Q9NV20
      UniProtKB/TrEMBL
      F2Z2V1

    20. XM_054337462.1 → XP_054193437.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F2Z2V1

    21. XM_054337461.1 → XP_054193436.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F2Z2V1

    22. XM_054337474.1 → XP_054193449.1  FGGY carbohydrate kinase domain-containing protein isoform X7

      UniProtKB/TrEMBL
      F2Z2V1

    23. XM_054337460.1 → XP_054193435.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F2Z2V1

    24. XM_054337465.1 → XP_054193440.1  FGGY carbohydrate kinase domain-containing protein isoform X2

      UniProtKB/Swiss-Prot
      B1AK92, B1AK93, B1AK94, B2RDR8, D3DQ56, Q96C11, Q9HA63, Q9NV20
      UniProtKB/TrEMBL
      F2Z2V1

    25. XM_054337472.1 → XP_054193447.1  FGGY carbohydrate kinase domain-containing protein isoform X6

      UniProtKB/TrEMBL
      F2Z2V1

    26. XM_054337455.1 → XP_054193430.1  FGGY carbohydrate kinase domain-containing protein isoform X1

      UniProtKB/TrEMBL
      F2Z2V1

    27. XM_054337480.1 → XP_054193455.1  FGGY carbohydrate kinase domain-containing protein isoform X9

    28. XM_054337468.1 → XP_054193443.1  FGGY carbohydrate kinase domain-containing protein isoform X3

      UniProtKB/TrEMBL
      F2Z2V1

    29. XM_054337482.1 → XP_054193457.1  FGGY carbohydrate kinase domain-containing protein isoform X9

    30. XM_054337486.1 → XP_054193461.1  FGGY carbohydrate kinase domain-containing protein isoform X9

    31. XM_054337481.1 → XP_054193456.1  FGGY carbohydrate kinase domain-containing protein isoform X9

    32. XM_054337476.1 → XP_054193451.1  FGGY carbohydrate kinase domain-containing protein isoform X8

    33. XM_054337479.1 → XP_054193454.1  FGGY carbohydrate kinase domain-containing protein isoform X9

    34. XM_054337484.1 → XP_054193459.1  FGGY carbohydrate kinase domain-containing protein isoform X9

    35. XM_054337487.1 → XP_054193462.1  FGGY carbohydrate kinase domain-containing protein isoform X10

    36. XM_054337475.1 → XP_054193450.1  FGGY carbohydrate kinase domain-containing protein isoform X8

    37. XM_054337489.1 → XP_054193464.1  FGGY carbohydrate kinase domain-containing protein isoform X11

    38. XM_054337488.1 → XP_054193463.1  FGGY carbohydrate kinase domain-containing protein isoform X11

    39. XM_054337494.1 → XP_054193469.1  FGGY carbohydrate kinase domain-containing protein isoform X14

    40. XM_054337490.1 → XP_054193465.1  FGGY carbohydrate kinase domain-containing protein isoform X11

    41. XM_054337491.1 → XP_054193466.1  FGGY carbohydrate kinase domain-containing protein isoform X11

    42. XM_054337493.1 → XP_054193468.1  FGGY carbohydrate kinase domain-containing protein isoform X13

    RNA

    1. XR_008486092.1 RNA Sequence

    2. XR_008486093.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q96C11.2 GenPept UniProtKB/Swiss-Prot:Q96C11

    Gene LinkOut

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