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    LINC01016 long intergenic non-protein coding RNA 1016 [ Homo sapiens (human) ]

    Gene ID: 100507584, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC01016provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 1016provided by HGNC
    Primary source
    HGNC:HGNC:48991
    See related
    Ensembl:ENSG00000249346 AllianceGenome:HGNC:48991
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Restricted expression toward testis (RPKM 9.8) See more
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    Genomic context

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    See LINC01016 in Genome Data Viewer
    Location:
    6p21.31
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (33889511..33896907, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (33710706..33718102, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (33857288..33864684, complement)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124901306 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33817822-33818352 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33820767-33821549 Neighboring gene uncharacterized LOC105375027 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24370 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33830758-33831258 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:33846380-33846880 Neighboring gene uncharacterized LOC105375026 Neighboring gene uncharacterized LOC107986590 Neighboring gene microRNA 7159 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24371 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24372

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. ETS-1-activated LINC01016 over-expression promotes tumor progression via suppression of RFFL-mediated DHX9 ubiquitination degradation in breast cancers. Sun Y, et al. Cell Death Dis, 2023 Aug 8. PMID 37550275, Free PMC Article
    2. Single-Molecule Sequencing Reveals Estrogen-Regulated Clinically Relevant lncRNAs in Breast Cancer. Jonsson P, et al. Mol Endocrinol, 2015 Nov. PMID 26426411, Free PMC Article
    3. Primate-specific oestrogen-responsive long non-coding RNAs regulate proliferation and viability of human breast cancer cells. Lin CY, et al. Open Biol, 2016 Dec. PMID 28003470, Free PMC Article
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ETS-1-activated LINC01016 over-expression promotes tumor progression via suppression of RFFL-mediated DHX9 ubiquitination degradation in breast cancers.
      Title: ETS-1-activated LINC01016 over-expression promotes tumor progression via suppression of RFFL-mediated DHX9 ubiquitination degradation in breast cancers.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_038989.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AK057709, AL138889, CR745530
      Related
      ENST00000506222.7

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

      Range
      33889511..33896907 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060930.1 Alternate T2T-CHM13v2.0

      Range
      33710706..33718102 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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