U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    api5 apoptosis inhibitor 5 [ Danio rerio (zebrafish) ]

    Gene ID: 321676, updated on 17-Aug-2024

    Summary

    Official Symbol
    api5provided by ZNC
    Official Full Name
    apoptosis inhibitor 5provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-395
    See related
    Ensembl:ENSDARG00000033597 AllianceGenome:ZFIN:ZDB-GENE-030131-395
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    api5l1; sr:nyz021; zgc:66211; wu:fb26c03
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in negative regulation of apoptotic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in nucleus. Is expressed in heart. Orthologous to human API5 (apoptosis inhibitor 5). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Location:
    chromosome: 25
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (30131045..30152213)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (29688038..29709206)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene TAFA chemokine like family member 5b Neighboring gene proline rich 5 like Neighboring gene si:ch211-147k10.6 Neighboring gene hydroxysteroid (17-beta) dehydrogenase 12a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199540.2NP_955834.2  apoptosis inhibitor 5

      Status: VALIDATED

      Source sequence(s)
      AW777998, CR376745, DY553207, EB928097, EH557238
      UniProtKB/TrEMBL
      A0A8M1PE19, R4GDP5
      Related
      ENSDARP00000126600.1, ENSDART00000152705.3
      Conserved Domains (1) summary
      pfam05918
      Location:5502
      API5; Apoptosis inhibitory protein 5 (API5)

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      30131045..30152213
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017354054.2XP_017209543.1  apoptosis inhibitor 5 isoform X1

      UniProtKB/TrEMBL
      A0A8M6Z4Y3