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    ajuba ajuba LIM protein [ Danio rerio (zebrafish) ]

    Gene ID: 572549, updated on 17-Aug-2024

    Summary

    Official Symbol
    ajubaprovided by ZNC
    Official Full Name
    ajuba LIM proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-9341
    See related
    Ensembl:ENSDARG00000077842 AllianceGenome:ZFIN:ZDB-GENE-030131-9341
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    jub; fj66b05; wu:fj66b05
    Summary
    Predicted to enable transcription corepressor activity. Acts upstream of or within heart development. Predicted to be part of transcription regulator complex. Predicted to be active in P-body; adherens junction; and nucleus. Is expressed in head. Orthologous to human AJUBA (ajuba LIM protein). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    Location:
    chromosome: 7
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (24100155..24112500, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (23829001..23841426, complement)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene embryonal Fyn-associated substrate Neighboring gene apoptotic chromatin condensation inducer 1b Neighboring gene mitochondrial ribosomal protein L52 Neighboring gene matrix metallopeptidase 14a (membrane-inserted)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within heart development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of hippo signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in response to hypoxia IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in P-body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in adherens junction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    protein ajuba; LIM domain-containing protein ajuba
    Names
    jub, ajuba homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      24100155..24112500 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_696274.9XP_701366.4  LIM domain-containing protein ajuba

      UniProtKB/TrEMBL
      A0A8N7TEU1, E7FFI0
      Related
      ENSDARP00000100146.2, ENSDART00000111923.5
      Conserved Domains (3) summary
      cd09352
      Location:486539
      LIM1_Ajuba_like; The first LIM domain of Ajuba-like proteins
      cd09355
      Location:551603
      LIM2_Ajuba_like; The second LIM domain of Ajuba-like proteins
      cd09438
      Location:611672
      LIM3_Ajuba_like; The third LIM domain of Ajuba-like proteins