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    YRO2 Yro2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852343, updated on 18-Sep-2024

    Summary

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    Official Symbol
    YRO2
    Official Full Name
    Yro2p
    Primary source
    SGD:S000000258
    Locus tag
    YBR054W
    See related
    AllianceGenome:SGD:S000000258; FungiDB:YBR054W; VEuPathDB:YBR054W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable ion channel activity. Predicted to be involved in ion transmembrane transport. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See YRO2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (343101..344135)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene flavodoxin-like fold family protein Neighboring gene uncharacterized protein Neighboring gene U4/U6-U5 snRNP complex subunit PRP6 Neighboring gene tRNA-Leu

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Homologues of archaeal rhodopsins in plants, animals and fungi: structural and functional predications for a putative fungal chaperone protein. Zhai Y, et al. Biochim Biophys Acta, 2001 Apr 2. PMID 11286964
    2. Plasma membrane proteins Yro2 and Mrh1 are required for acetic acid tolerance in Saccharomyces cerevisiae. Takabatake A, et al. Appl Microbiol Biotechnol, 2015 Mar. PMID 25503505
    3. Haa1, a protein homologous to the copper-regulated transcription factor Ace1, is a novel transcriptional activator. Keller G, et al. J Biol Chem, 2001 Oct 19. PMID 11504737
    4. Hsf1 activation inhibits rapamycin resistance and TOR signaling in yeast revealed by combined proteomic and genetic analysis. Bandhakavi S, et al. PLoS One, 2008 Feb 13. PMID 18270585, Free PMC Article
    5. Nuclear localization of Haa1, which is linked to its phosphorylation status, mediates lactic acid tolerance in Saccharomyces cerevisiae. Sugiyama M, et al. Appl Environ Microbiol, 2014 Jun. PMID 24682296, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Yro2 and Mrh1 are involved in tolerance to acetic acid stress.
      Title: Plasma membrane proteins Yro2 and Mrh1 are required for acetic acid tolerance in Saccharomyces cerevisiae.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cellular bud HDA PubMed 
    located_in endoplasmic reticulum HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Yro2p
    NP_009610.1
    • Protein with a putative role in response to acid stress; null mutant is sensitive to acetic acid; transcription is regulated by Haa1p and induced in the presence of acetic acid; protein observed in plasma membrane foci in the presence of acetic acid; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      343101..344135
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178402.1 → NP_009610.1  TPA: Yro2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009610.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQ53, P38079
      UniProtKB/TrEMBL
      A6ZKZ7, B3LN95, C7GSU0, G2W959, N1PAR8
      Conserved Domains (1) summary
      COG5524
      Location:4 → 290
      COG5524; Bacteriorhodopsin [Energy production and conversion, Signal transduction mechanisms]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38079.1

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