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    Tm9sf3 transmembrane 9 superfamily member 3 [ Mus musculus (house mouse) ]

    Gene ID: 107358, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Tm9sf3provided by MGI
    Official Full Name
    transmembrane 9 superfamily member 3provided by MGI
    Primary source
    MGI:MGI:1914262
    See related
    Ensembl:ENSMUSG00000025016 AllianceGenome:MGI:1914262
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Smbp; mKIAA4036; 1810073M23Rik; 2810031D16Rik
    Summary
    Predicted to be involved in protein localization to membrane. Predicted to be active in membrane. Is expressed in several structures, including brain; liver; muscle tissue; neural retina; and spleen. Orthologous to human TM9SF3 (transmembrane 9 superfamily member 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in placenta adult (RPKM 39.6), bladder adult (RPKM 34.8) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tm9sf3 in Genome Data Viewer
    Location:
    19 C3; 19 34.54 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (41199281..41252443, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (41210842..41264004, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:41103805-41103914 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:41105621-41105774 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:41113653-41113854 Neighboring gene STARR-seq mESC enhancer starr_46143 Neighboring gene STARR-positive B cell enhancer mm9_chr19:41146037-41146338 Neighboring gene STARR-seq mESC enhancer starr_46144 Neighboring gene deoxynucleotidyltransferase, terminal Neighboring gene oligodendrocytic myelin paranodal and inner loop protein Neighboring gene tolloid-like 2 Neighboring gene STARR-seq mESC enhancer starr_46145 Neighboring gene STARR-positive B cell enhancer ABC_E11676 Neighboring gene predicted gene, 54045 Neighboring gene phosphoinositide-3-kinase adaptor protein 1 Neighboring gene predicted gene, 52406 Neighboring gene STARR-positive B cell enhancer ABC_E8750 Neighboring gene STARR-positive B cell enhancer ABC_E11030 Neighboring gene STARR-positive B cell enhancer ABC_E2526 Neighboring gene STARR-positive B cell enhancer ABC_E7652 Neighboring gene STARR-positive B cell enhancer ABC_E7653 Neighboring gene STARR-seq mESC enhancer starr_46150 Neighboring gene STARR-positive B cell enhancer ABC_E7654 Neighboring gene predicted gene, 33951

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Comparative analysis of the expression patterns of TM9SF family members in mice. Zhao R, et al. Gene Expr Patterns, 2024 Jun. PMID 38719197
    2. Gene expression in the developing mouse retina by EST sequencing and microarray analysis. Mu X, et al. Nucleic Acids Res, 2001 Dec 15. PMID 11812828, Free PMC Article
    3. A global genomic transcriptional code associated with CNS-expressed genes. Bailey PJ, et al. Exp Cell Res, 2006 Oct 1. PMID 16919269
    4. Functional genomic landscape of cancer-intrinsic evasion of killing by T cells. Lawson KA, et al. Nature, 2020 Oct. PMID 32968282, Free PMC Article
    5. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • KIAA4036

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein localization to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane 9 superfamily member 3
    Names
    SM-11044 binding protein
    transmembrane protein 9 superfamily member 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133352.2 → NP_579930.1  transmembrane 9 superfamily member 3 precursor

      See identical proteins and their annotated locations for NP_579930.1

      Status: VALIDATED

      Source sequence(s)
      AC133099, AF269151, CA529050
      Consensus CDS
      CCDS29808.1
      UniProtKB/Swiss-Prot
      Q9ET30
      UniProtKB/TrEMBL
      A0A498WGK6
      Related
      ENSMUSP00000158318.2, ENSMUST00000237871.2
      Conserved Domains (1) summary
      pfam02990
      Location:56 → 525
      EMP70; Endomembrane protein 70

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      41199281..41252443 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_178146.2: Suppressed sequence

      Description
      NM_178146.2: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ET30.1 GenPept UniProtKB/Swiss-Prot:Q9ET30

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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