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    YPT10 Rab family GTPase YPT10 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852567, updated on 18-Sep-2024

    Summary

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    Official Symbol
    YPT10
    Official Full Name
    Rab family GTPase YPT10
    Primary source
    SGD:S000000468
    Locus tag
    YBR264C
    See related
    AllianceGenome:SGD:S000000468; FungiDB:YBR264C; VEuPathDB:YBR264C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables guanyl nucleotide binding activity. Involved in Golgi organization. Located in fungal-type vacuole membrane. Orthologous to human RAB24 (RAB24, member RAS oncogene family). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See YPT10 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (737770..738369, complement)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Mic12p Neighboring gene glycine hydroxymethyltransferase SHM1 Neighboring gene 3-dehydrosphinganine reductase Neighboring gene Rei1p Neighboring gene Slm6p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the ORF YBR264c in Saccharomyces cerevisiae, which encodes a new yeast Ypt that is degraded by a proteasome-dependent mechanism. Louvet O, et al. Mol Gen Genet, 1999 Jun. PMID 10394895
    2. The complete sequence of a 19,482 bp segment located on the right arm of chromosome II from Saccharomyces cerevisiae. Doignon F, et al. Yeast, 1993 Feb. PMID 8465606
    3. Bioinformatic and comparative localization of Rab proteins reveals functional insights into the uncharacterized GTPases Ypt10p and Ypt11p. Buvelot Frei S, et al. Mol Cell Biol, 2006 Oct. PMID 16980630, Free PMC Article
    4. Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins. Calero M, et al. Biochem Biophys Res Commun, 2002 Jan 18. PMID 11785952
    5. Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors. Calero M, et al. FEBS Lett, 2002 Mar 27. PMID 11943201

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables guanyl nucleotide binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Golgi organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in fungal-type vacuole membrane HDA PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Rab family GTPase YPT10
    NP_009823.2
    • Rab family GTP-binding protein; contains the PEST signal sequence specific for proteolytic enzymes; may be involved in vesicular transport; overexpression leads to accumulation of Golgi-like cisternae with budding vesicles

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      737770..738369 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178612.1 → NP_009823.2  TPA: Rab family GTPase YPT10 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009823.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQR1, P38146
      UniProtKB/TrEMBL
      A6ZLK4, B3LMP7, C7GMW6, N1PAW3
      Conserved Domains (1) summary
      cd00154
      Location:5 → 158
      Rab; Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38146.2

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