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    RPS13 ribosomal 40S subunit protein S13 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851636, updated on 4-Aug-2024

    Summary

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    Gene symbol
    RPS13
    Gene description
    ribosomal 40S subunit protein S13
    Primary source
    FungiDB:YDR064W
    Locus tag
    YDR064W
    See related
    SGD:S000002471; AllianceGenome:SGD:S000002471; VEuPathDB:YDR064W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RPS13B; RPS13C
    Summary
    Enables small ribosomal subunit rRNA binding activity. A structural constituent of ribosome. Involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Part of cytosolic small ribosomal subunit. Orthologous to human RPS13 (ribosomal protein S13). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RPS13 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    2
    Sequence:
    Chromosome: IV; NC_001136.10 (579458..580452)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene serine C-palmitoyltransferase LCB2 Neighboring gene Aim7p Neighboring gene Rrg1p Neighboring gene putative protein-serine/threonine phosphatase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of proteins crosslinked to RNA in 40S ribosomal subunits of Saccharomyces cerevisiae. Xiang RH, et al. Biochimie, 1989 Nov-Dec. PMID 2517480
    2. Yeast Upf1 CH domain interacts with Rps26 of the 40S ribosomal subunit. Min EE, et al. RNA, 2013 Aug. PMID 23801788, Free PMC Article
    3. Yeast Swd2 is essential because of antagonism between Set1 histone methyltransferase complex and APT (associated with Pta1) termination factor. Soares LM, et al. J Biol Chem, 2012 May 4. PMID 22431730, Free PMC Article
    4. Protein topography of the 40 S ribosomal subunit from Saccharomyces cerevisiae as shown by chemical cross-linking. Yeh YC, et al. J Biol Chem, 1986 Oct 25. PMID 3533916
    5. Repressed synthesis of ribosomal proteins generates protein-specific cell cycle and morphological phenotypes. Thapa M, et al. Mol Biol Cell, 2013 Dec. PMID 24109599, Free PMC Article

    See all (97) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data suggest that ecruitment of COMPASS subunits PMA1 and RPS13 is dependent upon Set1 and Swd2, a subunit of the essential transcription termination factor APT (associated with Pta1).
      Title: Yeast Swd2 is essential because of antagonism between Set1 histone methyltransferase complex and APT (associated with Pta1) termination factor.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables small ribosomal subunit rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables small ribosomal subunit rRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of 90S preribosome HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 40S subunit protein S13
    NP_010349.3
    • Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S13 and bacterial S15

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      579458..580452
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180372.3 → NP_010349.3  TPA: ribosomal 40S subunit protein S13 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010349.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VS50, P05756
      UniProtKB/TrEMBL
      A6ZY29, C8Z4Y3, G2WAG8, N1PAC5
      Conserved Domains (1) summary
      PTZ00072
      Location:4 → 151
      PTZ00072; 40S ribosomal protein S13; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P05756.3

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