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    RPA34 DNA-directed RNA polymerase I subunit RPA34 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853293, updated on 29-Jun-2024

    Summary

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    Gene symbol
    RPA34
    Gene description
    DNA-directed RNA polymerase I subunit RPA34
    Primary source
    FungiDB:YJL148W
    Locus tag
    YJL148W
    See related
    SGD:S000003684; AllianceGenome:SGD:S000003684; VEuPathDB:YJL148W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    CST21
    Summary
    Contributes to RNA polymerase I activity. Involved in nucleolar large rRNA transcription by RNA polymerase I and transcription elongation from RNA polymerase I promoter. Located in nucleolus. Part of RNA polymerase I complex. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RPA34 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (140437..141138)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Smt1p Neighboring gene Ids2p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Further characterization of yeast RNA polymerases. Effect of subunits removal. Huet J, et al. Biochimie, 1976. PMID 182285
    2. Characterization of ribonuclease H activity associated yeast RNA polymerase A. Huet J, et al. J Biol Chem, 1977 Dec 25. PMID 21884
    3. Prefoldin-like Bud27 influences the transcription of ribosomal components and ribosome biogenesis in Saccharomyces cerevisiae. Martínez-Fernández V, et al. RNA, 2020 Oct. PMID 32503921, Free PMC Article
    4. Deletion of Rnt1p alters the proportion of open versus closed rRNA gene repeats in yeast. Catala M, et al. Mol Cell Biol, 2008 Jan. PMID 17991894, Free PMC Article
    5. Localization of the yeast RNA polymerase I-specific subunits. Bischler N, et al. EMBO J, 2002 Aug 1. PMID 12145213, Free PMC Article

    See all (110) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    contributes_to RNA polymerase I activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nucleolar large rRNA transcription by RNA polymerase I IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transcription by RNA polymerase I IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transcription elongation by RNA polymerase I IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of DNA-directed RNA polymerase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of RNA polymerase I complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of RNA polymerase I complex IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA-directed RNA polymerase I subunit RPA34
    NP_012387.1
    • RNA polymerase I subunit A34.5; essential for nucleolar assembly and for high polymerase loading rate; nucleolar localization depends on Rpa49p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      140437..141138
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181581.1 → NP_012387.1  TPA: DNA-directed RNA polymerase I subunit RPA34 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012387.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VW37, P47006
      UniProtKB/TrEMBL
      A0A8H4BYA5, A6ZQI2, C7GPY3, D3UF52, N1P0G1
      Conserved Domains (1) summary
      pfam08208
      Location:52 → 198
      RNA_polI_A34; DNA-directed RNA polymerase I subunit RPA34.5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P47006.1

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