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    CWP2 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853765, updated on 11-Sep-2024

    Summary

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    Official Symbol
    CWP2
    Primary source
    SGD:S000001956
    Locus tag
    YKL096W-A
    See related
    AllianceGenome:SGD:S000001956; FungiDB:YKL096W-A; VEuPathDB:YKL096W-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    LPR1; YKL097W-A
    Summary
    A structural constituent of cell wall. Involved in fungal-type cell wall organization. Located in fungal-type cell wall. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (259253..259531)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cwp1p Neighboring gene mRNA splicing protein YJU2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Improved cellulase production in recombinant Saccharomyces cerevisiae by disrupting the cell wall protein-encoding gene CWP2. Li J, et al. J Biosci Bioeng, 2020 Feb. PMID 31537451
    2. Dominant suppressor mutation bypasses the sphingolipid requirement for growth of Saccharomyces cells at low pH: role of the CWP2 gene. Skrzypek M, et al. Curr Genet, 2000 Nov. PMID 11126778
    3. Suppressor gene analysis reveals an essential role for sphingolipids in transport of glycosylphosphatidylinositol-anchored proteins in Saccharomyces cerevisiae. Skrzypek M, et al. J Bacteriol, 1997 Mar. PMID 9045807, Free PMC Article
    4. The retention mechanism of cell wall proteins in Saccharomyces cerevisiae. Wall-bound Cwp2p is beta-1,6-glucosylated. van der Vaart JM, et al. Biochim Biophys Acta, 1996 Dec 6. PMID 8980634
    5. DNA sequence analysis of a 17 kb fragment of yeast chromosome XI physically localizes the MRB1 gene and reveals eight new open reading frames, including a homologue of the KIN1/KIN2 and SNF1 protein kinases. Pallier C, et al. Yeast, 1993 Oct. PMID 8256524

    See all (59) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of cell wall IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in fungal-type cell wall organization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in fungal-type cell wall organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cwp2p
    NP_012826.1
    • Covalently linked cell wall mannoprotein; major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      259253..259531
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180025.1 → NP_012826.1  TPA: Cwp2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012826.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VXJ1, P43497
      UniProtKB/TrEMBL
      A6ZZM0, B3LQZ7, B5VM61, C7GVL3, C8ZC78, G2WHT7, N1P7R2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P43497.1

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