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    RCI50 Rci50p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853725, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RCI50
    Official Full Name
    Rci50p
    Primary source
    SGD:S000001616
    Locus tag
    YKL133C
    See related
    AllianceGenome:SGD:S000001616; FungiDB:YKL133C; VEuPathDB:YKL133C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable misfolded protein binding activity. Predicted to be involved in protein quality control for misfolded or incompletely synthesized proteins. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RCI50 in Genome Data Viewer
    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (191679..193070, complement)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene Apl2p Neighboring gene metalloendopeptidase Neighboring gene putative tetrahydrofolate synthase Neighboring gene She2p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mgr3p and Mgr1p are adaptors for the mitochondrial i-AAA protease complex. Dunn CD, et al. Mol Biol Cell, 2008 Dec. PMID 18843051, Free PMC Article
    2. Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale. Morgenstern M, et al. Cell Rep, 2017 Jun 27. PMID 28658629, Free PMC Article
    3. Rcf1 mediates cytochrome oxidase assembly and respirasome formation, revealing heterogeneity of the enzyme complex. Vukotic M, et al. Cell Metab, 2012 Mar 7. PMID 22342701
    4. Kel1 is a phosphorylation-regulated noise suppressor of the pheromone signaling pathway. Garcia I, et al. Cell Rep, 2021 Dec 28. PMID 34965431
    5. A complex of Cox4 and mitochondrial Hsp70 plays an important role in the assembly of the cytochrome c oxidase. Böttinger L, et al. Mol Biol Cell, 2013 Sep. PMID 23864706, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables misfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in protein quality control for misfolded or incompletely synthesized proteins IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of i-AAA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    Rci50p
    NP_012789.2
    • Mitochondrial hypothetical protein; not required for growth of cells lacking the mitochondrial genome; SWAT-GFP and mCherry fusion proteins localize to the mitochondria; YKL133C has a paralog, MGR3, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      191679..193070 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179699.2 → NP_012789.2  TPA: Rci50p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012789.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VX63, P36066
      UniProtKB/TrEMBL
      A6ZZI8, B3LQW7, C7GVI3, N1P8C6
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P36066.2

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