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    RPL33B ribosomal 60S subunit protein L33B [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854409, updated on 29-Jun-2024

    Summary

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    Gene symbol
    RPL33B
    Gene description
    ribosomal 60S subunit protein L33B
    Primary source
    FungiDB:YOR234C
    Locus tag
    YOR234C
    See related
    SGD:S000005760; AllianceGenome:SGD:S000005760; VEuPathDB:YOR234C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RPL37B
    Summary
    A structural constituent of ribosome. Involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 5. Orthologous to human RPL35A (ribosomal protein L35a). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RPL33B in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    2
    Sequence:
    Chromosome: XV; NC_001147.6 (778555..779405, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Mge1p Neighboring gene putative serine/threonine protein kinase KIN4 Neighboring gene Irc13p Neighboring gene ncRNA Neighboring gene dihydrofolate reductase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Saccharomyces cerevisiae ribosomal protein L37 is encoded by duplicate genes that are differentially expressed. Tornow J, et al. Curr Genet, 1994 Jun. PMID 8082197
    2. Introns within ribosomal protein genes regulate the production and function of yeast ribosomes. Parenteau J, et al. Cell, 2011 Oct 14. PMID 22000012
    3. A High-Copy Suppressor Screen Reveals a Broad Role of Prefoldin-like Bud27 in the TOR Signaling Pathway in Saccharomyces cerevisiae. Gutiérrez-Santiago F, et al. Genes (Basel), 2022 Apr 24. PMID 35627133, Free PMC Article
    4. Yeast ribosomal proteins. VIII. Isolation of two proteins and sequence characterization of twenty-four proteins from cytoplasmic ribosomes. Otaka E, et al. Mol Gen Genet, 1984. PMID 18782943
    5. Novel interactions of Saccharomyces cerevisiae type 1 protein phosphatase identified by single-step affinity purification and mass spectrometry. Walsh EP, et al. Biochemistry, 2002 Feb 19. PMID 11841235

    See all (65) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cytoplasmic translation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in ribosomal large subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 60S subunit protein L33B
    NP_014877.3
    • Ribosomal 60S subunit protein L33B; rpl33b null mutant exhibits normal growth while rpl33a rpl33b double null mutant is inviable; homologous to mammalian ribosomal protein L35A, no bacterial homolog; RPL33B has a paralog, RPL33A, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      778555..779405 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183653.3 → NP_014877.3  TPA: ribosomal 60S subunit protein L33B [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014877.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2T8, P41056
      UniProtKB/TrEMBL
      A6ZP75, C8ZGY8, G2WNA4, N1NVW4
      Conserved Domains (1) summary
      pfam01247
      Location:7 → 100
      Ribosomal_L35Ae; Ribosomal protein L35Ae
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P41056.2

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