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    YOR283W phosphoglycerate mutase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854457, updated on 1-Aug-2024

    Summary

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    Gene symbol
    YOR283W
    Gene description
    phosphoglycerate mutase
    Primary source
    FungiDB:YOR283W
    Locus tag
    YOR283W
    See related
    SGD:S000005809; AllianceGenome:SGD:S000005809; VEuPathDB:YOR283W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables phosphatase activity. Involved in dephosphorylation. Located in cytoplasm and nucleus. Orthologous to human TIGAR (TP53 induced glycolysis regulatory phosphatase). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See YOR283W in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (847453..848145)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene putative serine hydrolase Neighboring gene Plp2p Neighboring gene Hua2p Neighboring gene thiosulfate sulfurtransferase RDL1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure and activity of the metal-independent fructose-1,6-bisphosphatase YK23 from Saccharomyces cerevisiae. Kuznetsova E, et al. J Biol Chem, 2010 Jul 2. PMID 20427268, Free PMC Article
    2. Identification of nucleases and phosphatases by direct biochemical screen of the Saccharomyces cerevisiae proteome. Ho CK, et al. PLoS One, 2009 Sep 15. PMID 19753119, Free PMC Article
    3. Fungal BLAST and Model Organism BLASTP Best Hits: new comparison resources at the Saccharomyces Genome Database (SGD). Balakrishnan R, et al. Nucleic Acids Res, 2005 Jan 1. PMID 15608219, Free PMC Article
    4. The oxysterol binding protein Kes1p regulates Golgi apparatus phosphatidylinositol-4-phosphate function. Fairn GD, et al. Proc Natl Acad Sci U S A, 2007 Sep 25. PMID 17881569, Free PMC Article
    5. Integrating high-throughput genetic interaction mapping and high-content screening to explore yeast spindle morphogenesis. Vizeacoumar FJ, et al. J Cell Biol, 2010 Jan 11. PMID 20065090, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in dephosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    phosphoglycerate mutase
    NP_014926.1
    • Phosphatase with a broad substrate specificity; has some similarity to GPM1/YKL152C, a phosphoglycerate mutase; YOR283W is not an essential gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      847453..848145
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183702.1 → NP_014926.1  TPA: phosphoglycerate mutase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014926.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2Y1, Q12040
      UniProtKB/TrEMBL
      A6ZPB8, B3LJU7, B5VSG2, C7GWA9, C8ZH33, G2WNE9, N1NXD2
      Conserved Domains (1) summary
      pfam00300
      Location:19 → 214
      His_Phos_1; Histidine phosphatase superfamily (branch 1)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12040.1

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