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    BUD7 exomer complex subunit [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854475, updated on 1-Aug-2024

    Summary

    Gene symbol
    BUD7
    Gene description
    exomer complex subunit
    Primary source
    FungiDB:YOR299W
    Locus tag
    YOR299W
    See related
    SGD:S000005825; AllianceGenome:SGD:S000005825; VEuPathDB:YOR299W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in Golgi to plasma membrane transport; cellular bud site selection; and fungal-type cell wall chitin biosynthetic process. Part of exomer complex. Colocalizes with trans-Golgi network transport vesicle. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See BUD7 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (878435..880675)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Mum3p Neighboring gene multiprotein-bridging factor 1 Neighboring gene Rax1p Neighboring gene uncharacterized protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in Golgi to plasma membrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in Golgi to plasma membrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in Golgi to plasma membrane transport IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in cellular bud site selection IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in chitin biosynthetic process IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of exomer complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of exomer complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of exomer complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in trans-Golgi network transport vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    exomer complex subunit
    NP_014943.1
    • Member of the ChAPs family (Chs5p-Arf1p-binding proteins); members include Bch1p, Bch2p, Bud7p, and Chs6p; ChAPs family proteins form the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane; BUD7 has a paralog, BCH1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      878435..880675
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183718.1NP_014943.1  TPA: exomer complex subunit [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014943.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2Z9, Q08754
      UniProtKB/TrEMBL
      B3LJW4, C7GNW1, N1NXF5
      Conserved Domains (2) summary
      sd00006
      Location:371400
      TPR; TPR repeat [structural motif]
      pfam09295
      Location:123533
      ChAPs; ChAPs (Chs5p-Arf1p-binding proteins)