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    thbs3a thrombospondin 3a [ Danio rerio (zebrafish) ]

    Gene ID: 252849, updated on 9-Dec-2024

    Summary

    Official Symbol
    thbs3aprovided by ZNC
    Official Full Name
    thrombospondin 3aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-020708-3
    See related
    Ensembl:ENSDARG00000077641 AllianceGenome:ZFIN:ZDB-GENE-020708-3
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    tsp3; thbs3; zgc:103461
    Summary
    Predicted to enable calcium ion binding activity. Acts upstream of or within mesenchymal to epithelial transition and somite development. Predicted to be located in extracellular region. Predicted to be active in collagen-containing extracellular matrix. Is expressed in several structures, including brain; ectoderm; epidermis; pectoral fin; and pharyngeal arch. Orthologous to human THBS3 (thrombospondin 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See thbs3a in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (42900238..42933322, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (42996480..43029509, complement)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene hemojuvelin BMP co-receptor Neighboring gene microRNA 92b Neighboring gene metaxin 1a Neighboring gene TEX13 family member C Neighboring gene uncharacterized LOC101886004

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC103461

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within mesenchymal to epithelial transition IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within somite development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in collagen-containing extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    thrombospondin-3a
    Names
    Tsp-3a

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173225.2NP_775332.2  thrombospondin-3a precursor

      Status: VALIDATED

      Source sequence(s)
      CR854827
      UniProtKB/Swiss-Prot
      Q5U3J1, Q8JHW2
      Related
      ENSDARP00000057304.6, ENSDART00000057305.7

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      42900238..42933322 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)