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    znf76 zinc finger protein 76 [ Danio rerio (zebrafish) ]

    Gene ID: 564210, updated on 4-Jan-2025

    Summary

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    Official Symbol
    znf76provided by ZNC
    Official Full Name
    zinc finger protein 76provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061027-379
    See related
    Ensembl:ENSDARG00000013279 AllianceGenome:ZFIN:ZDB-GENE-061027-379
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:153635
    Summary
    Predicted to enable metal ion binding activity. Is expressed in brain; eye; gut; and trigeminal placode. Orthologous to human ZNF76 (zinc finger protein 76). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See znf76 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (737211..753395)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (699498..715672)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene ADP-ribosylation factor-like 8A Neighboring gene zgc:162255 Neighboring gene retinoblastoma binding protein 5 Neighboring gene cryptochrome circadian regulator 3b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Znf76 is associated with development of the eyes, midbrain, MHB, and hindbrain in zebrafish embryos. Jung J, et al. Anim Cells Syst (Seoul), 2019 Feb. PMID 30834156, Free PMC Article
    2. march5 Governs the Convergence and Extension Movement for Organization of the Telencephalon and Diencephalon in Zebrafish Embryos. Jung J, et al. Mol Cells, 2020 Jan 31. PMID 31910335, Free PMC Article
    3. Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. Diotel N, et al. J Comp Neurol, 2015 Jun 1. PMID 25556858, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC153635

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 76

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077610.1 → NP_001071078.1  zinc finger protein 76

      See identical proteins and their annotated locations for NP_001071078.1

      Status: PROVISIONAL

      Source sequence(s)
      BC124408
      UniProtKB/TrEMBL
      B2GS63, Q05AL8
      Related
      ENSDARP00000020208.7, ENSDART00000017305.8
      Conserved Domains (3) summary
      sd00017
      Location:170 → 192
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:244 → 271
      zf-H2C2_2; Zinc-finger double domain
      pfam17017
      Location:228 → 349
      zf-C2H2_aberr; Aberrant zinc-finger

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      737211..753395
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068216332.1 → XP_068072433.1  zinc finger protein 76 isoform X2

      UniProtKB/TrEMBL
      B2GS63, Q05AL8

    2. XM_009295759.3 → XP_009294034.1  zinc finger protein 76 isoform X1

      UniProtKB/TrEMBL
      A0A8M3AUB7
      Conserved Domains (3) summary
      sd00017
      Location:188 → 210
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:262 → 289
      zf-H2C2_2; Zinc-finger double domain
      pfam17017
      Location:246 → 367
      zf-C2H2_aberr; Aberrant zinc-finger

    3. XM_009295760.4 → XP_009294035.1  zinc finger protein 76 isoform X2

      See identical proteins and their annotated locations for XP_009294035.1

      UniProtKB/TrEMBL
      B2GS63, Q05AL8
      Conserved Domains (3) summary
      sd00017
      Location:170 → 192
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:244 → 271
      zf-H2C2_2; Zinc-finger double domain
      pfam17017
      Location:228 → 349
      zf-C2H2_aberr; Aberrant zinc-finger
    Nucleotide Protein Strain
    Heading Accession and Version

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