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    si:ch73-343l4.8 si:ch73-343l4.8 [ Danio rerio (zebrafish) ]

    Gene ID: 100320176, updated on 9-Dec-2024

    Summary

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    Official Symbol
    si:ch73-343l4.8provided by ZNC
    Official Full Name
    si:ch73-343l4.8provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090313-159
    See related
    Ensembl:ENSDARG00000077975 AllianceGenome:ZFIN:ZDB-GENE-090313-159
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable D-mannose binding activity; fucose binding activity; and pattern recognition receptor activity. Predicted to be involved in immune response. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Orthologous to human CLEC4F (C-type lectin domain family 4 member F). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See si:ch73-343l4.8 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (55891376..55896332, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (55213789..55218681, complement)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b Neighboring gene anti-silencing function 1Bb histone chaperone Neighboring gene uncharacterized LOC103909412 Neighboring gene CD209 antigen

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables pattern recognition receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    C-type lectin domain family 4 member E

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      55891376..55896332 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002660579.6 → XP_002660625.1  C-type lectin domain family 4 member E

      UniProtKB/TrEMBL
      A0A8M1RJW6, B8JM30
      Related
      ENSDARP00000121395.1, ENSDART00000147516.2
      Conserved Domains (1) summary
      cd03590
      Location:48 → 170
      CLECT_DC-SIGN_like; C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR)
    Nucleotide Protein Strain
    Heading Accession and Version

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