nup43 nucleoporin 43 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: nup43provided by ZNC
Official Full Name: nucleoporin 43provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2533
See related: Ensembl:ENSDARG00000043884 AllianceGenome:ZFIN:ZDB-GENE-040426-2533
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:77032
Summary: Acts upstream of or within heart development. Predicted to be part of nuclear pore outer ring. Is expressed in alar plate midbrain region; eye; immature eye; optic tectum; and pharyngeal arch. Orthologous to human NUP43 (nucleoporin 43). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (1316733..1327859)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (1295907..1307033)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within heart development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of nuclear pore outer ring	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: nucleoporin Nup43

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_212892.1 → NP_998057.1 nucleoporin Nup43

See identical proteins and their annotated locations for NP_998057.1

Status: PROVISIONAL

Source sequence(s)

BC066616

UniProtKB/TrEMBL

Q6NYF4

Related

ENSDARP00000064438.4, ENSDART00000064439.6

Conserved Domains (3) summary

COG2319
Location:138 → 361

WD40; WD40 repeat [General function prediction only]

sd00039
Location:170 → 209

7WD40; WD40 repeat [structural motif]

cl02567
Location:73 → 294

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...