usf2 upstream transcription factor 2, c-fos interacting [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: usf2provided by ZNC
Official Full Name: upstream transcription factor 2, c-fos interactingprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-8475
See related: Ensembl:ENSDARG00000020228 AllianceGenome:ZFIN:ZDB-GENE-030131-8475
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb12g11; wu:fb12g11; si:dkey-211g8.3
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Orthologous to human USF2 (upstream transcription factor 2, c-fos interacting). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (10558994..10577420)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (10639456..10658495)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: upstream stimulatory factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001122785.1 → NP_001116257.1 upstream stimulatory factor 2

Status: PROVISIONAL

Source sequence(s)

CR384101

UniProtKB/TrEMBL

A0A8M1NFY5, Q1L959

Related

ENSDARP00000116833.1, ENSDART00000148353.3

Conserved Domains (2) summary

cd00083
Location:216 → 278

HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

pfam05615
Location:273 → 317

THOC7; Tho complex subunit 7

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007130.7 Reference GRCz11 Primary Assembly

Range

10558994..10577420

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005159453.5 → XP_005159510.1 upstream stimulatory factor 2 isoform X2

UniProtKB/TrEMBL

A0A8M2B609

Conserved Domains (2) summary

cd00083
Location:201 → 263

HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

pfam05615
Location:258 → 302

THOC7; Tho complex subunit 7
XM_021468099.2 → XP_021323774.1 upstream stimulatory factor 2 isoform X1

UniProtKB/TrEMBL

A0A8M9PGH7

Conserved Domains (1) summary

cd00083
Location:208 → 270

HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...