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    krt15 keratin 15 [ Danio rerio (zebrafish) ]

    Gene ID: 406844, updated on 9-Dec-2024

    Summary

    Official Symbol
    krt15provided by ZNC
    Official Full Name
    keratin 15provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2931
    See related
    Ensembl:ENSDARG00000036840 AllianceGenome:ZFIN:ZDB-GENE-040426-2931
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:55334; wu:fa91c06; wu:fa95d04
    Summary
    Predicted to enable structural molecule activity. Predicted to be located in intermediate filament. Predicted to be active in cytoskeleton. Is expressed in digestive system; lateral line system; and trunk. Human ortholog(s) of this gene implicated in Meesmann corneal dystrophy 1; corneal dystrophy; epidermolytic hyperkeratosis; and epidermolytic hyperkeratosis 2. Orthologous to several human genes including KRT15 (keratin 15). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See krt15 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (11515778..11518475, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (11532157..11534854, complement)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene keratin 94 Neighboring gene keratin 98 Neighboring gene uncharacterized LOC137490406 Neighboring gene keratin 99

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in intermediate filament IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    keratin, type I cytoskeletal 15
    Names
    cytokeratin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213523.2NP_998688.2  keratin, type I cytoskeletal 15

      Status: VALIDATED

      Source sequence(s)
      CR556712, EH115385, EH448300, EH452973, EH471533
      UniProtKB/TrEMBL
      A0A8M1PJL5, B0UYS0
      Related
      ENSDARP00000095029.4, ENSDART00000104254.5
      Conserved Domains (1) summary
      pfam00038
      Location:106413
      Filament; Intermediate filament protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      11515778..11518475 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394802.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      15399..18096 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)