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    srp68 signal recognition particle 68 [ Danio rerio (zebrafish) ]

    Gene ID: 446119, updated on 2-Nov-2024

    Summary

    Official Symbol
    srp68provided by ZNC
    Official Full Name
    signal recognition particle 68provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040831-3
    See related
    Ensembl:ENSDARG00000020820 AllianceGenome:ZFIN:ZDB-GENE-040831-3
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:92573
    Summary
    Predicted to enable signal recognition particle binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be located in cytoplasm and nucleolus. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Human ortholog(s) of this gene implicated in severe congenital neutropenia. Orthologous to human SRP68 (signal recognition particle 68). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See srp68 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (23026714..23055092)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (17928795..17957173)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene transfer RNA arginine (anticodon CCG) Neighboring gene polymerase (DNA directed), gamma 2, accessory subunit Neighboring gene envoplakin a Neighboring gene TEN1 subunit of CST complex

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables 7S RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables endoplasmic reticulum signal peptide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables signal recognition particle binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables signal recognition particle binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of signal recognition particle, endoplasmic reticulum targeting IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of signal recognition particle, endoplasmic reticulum targeting IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    signal recognition particle subunit SRP68
    Names
    signal recognition particle 68kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005401.3NP_001005401.2  signal recognition particle subunit SRP68

      See identical proteins and their annotated locations for NP_001005401.2

      Status: VALIDATED

      Source sequence(s)
      CR450715
      UniProtKB/TrEMBL
      A0A8M1N2E8, A7YYE9, F1QI99
      Related
      ENSDARP00000111715.3, ENSDART00000124948.3
      Conserved Domains (1) summary
      pfam16969
      Location:42563
      SRP68; RNA-binding signal recognition particle 68

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      23026714..23055092
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)