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    srrm1 serine/arginine repetitive matrix 1 [ Danio rerio (zebrafish) ]

    Gene ID: 406751, updated on 9-Dec-2024

    Summary

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    Official Symbol
    srrm1provided by ZNC
    Official Full Name
    serine/arginine repetitive matrix 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2789
    See related
    Ensembl:ENSDARG00000001244 AllianceGenome:ZFIN:ZDB-GENE-040426-2789
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:63802; wu:fb34f04; wu:fb38b06
    Summary
    Predicted to be involved in regulation of mRNA splicing, via spliceosome. Predicted to act upstream of or within mRNA processing. Predicted to be part of spliceosomal complex. Orthologous to human SRRM1 (serine and arginine repetitive matrix 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See srrm1 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (25426091..25440353)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (25407680..25421962)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene zgc:154055 Neighboring gene L-threonine dehydrogenase 2 Neighboring gene chloride intracellular channel 4 Neighboring gene crystallin beta-gamma domain containing 1a Neighboring gene reticulon 4 interacting protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A novel protein domain in an ancestral splicing factor drove the evolution of neural microexons. Torres-Méndez A, et al. Nat Ecol Evol, 2019 Apr. PMID 30833759
    2. Processing of fish Ig heavy chain transcripts: diverse splicing patterns and unusual nonsense mediated decay. Quiniou SM, et al. Dev Comp Immunol, 2011 Sep. PMID 21168434
    3. Reconstruction of a 450-My-old ancestral vertebrate protokaryotype. Kohn M, et al. Trends Genet, 2006 Apr. PMID 16517001
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    serine/arginine repetitive matrix protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001365281.1 → NP_001352210.1  serine/arginine repetitive matrix protein 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      CU972452
      UniProtKB/TrEMBL
      A0A8M2B5D0, E7F1X7, Q6PEG8
      Related
      ENSDARP00000111346.1, ENSDART00000121848.3
      Conserved Domains (2) summary
      pfam01480
      Location:46 → 115
      PWI; PWI domain
      cl28033
      Location:469 → 786
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

    2. NM_213442.2 → NP_998607.2  serine/arginine repetitive matrix protein 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      CU972452
      UniProtKB/TrEMBL
      Q6PEG8
      Related
      ENSDARP00000124762.1, ENSDART00000149241.3
      Conserved Domains (2) summary
      pfam01480
      Location:46 → 115
      PWI; PWI domain
      cl28033
      Location:469 → 786
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      25426091..25440353
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068214380.1 → XP_068070481.1  serine/arginine repetitive matrix protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B4V6, Q6PEG8
    Nucleotide Protein Strain
    Heading Accession and Version

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