gpc1b glypican 1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gpc1bprovided by ZNC
Official Full Name: glypican 1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1306
See related: Ensembl:ENSDARG00000090585 AllianceGenome:ZFIN:ZDB-GENE-040426-1306
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: gpc1; zgc:63947; im:7148416
Summary: Predicted to enable fibroblast growth factor binding activity. Predicted to be involved in cell migration; negative regulation of fibroblast growth factor receptor signaling pathway; and regulation of protein localization to membrane. Predicted to act upstream of or within regulation of signal transduction. Predicted to be located in several cellular components, including collagen-containing extracellular matrix; extracellular region; and side of membrane. Predicted to be active in cell surface and synapse. Is expressed in several structures, including ectoderm; epidermis; nervous system; pharyngeal arch; and ventral mesenchyme. Orthologous to human GPC1 (glypican 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 2

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (46032550..46188632)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (46179680..46331772)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables fibroblast growth factor binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in cell migration	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of fibroblast growth factor receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of protein localization to membrane	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cell surface	IBA Inferred from Biological aspect of Ancestor more info
located_in collagen-containing extracellular matrix	IEA Inferred from Electronic Annotation more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in side of membrane	IEA Inferred from Electronic Annotation more info
is_active_in synapse	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: glypican-1b

Names: glypican 1; heparan sulfate proteoglycan

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.