rasl11b RAS-like, family 11, member B [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rasl11bprovided by ZNC
Official Full Name: RAS-like, family 11, member Bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-793
See related: Ensembl:ENSDARG00000015611 AllianceGenome:ZFIN:ZDB-GENE-040426-793
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fc21f04; zgc:55750; zgc:77749; wu:fc21f04
Summary: Predicted to enable G protein activity and GTP binding activity. Acts upstream of or within mesendoderm development. Is expressed in several structures, including axis; central nervous system; presumptive ectoderm; shield; and tail bud. Orthologous to human RASL11B (RAS like family 11 member B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (23022985..23026223, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (23123885..23127123, complement)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Rasl11b modifies the effect of Oep on mesendoderm development independently of the main known Oep output: the Nodal signaling pathway
Title: Rasl11b knock down in zebrafish suppresses one-eyed-pinhead mutant phenotype.

Submit: New GeneRIF Correction

General gene information

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Markers

fc21f04.x1 (e-PCR)
- UniSTS:203868

fc21f04.x1 (e-PCR)
- UniSTS:187804

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables G protein activity	IEA Inferred from Electronic Annotation more info
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within mesendoderm development	IGI Inferred from Genetic Interaction more info	PubMed

General protein information

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Preferred Names: ras-like protein family member 11B

NP_956434.1

EC 3.6.5.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200140.1 → NP_956434.1 ras-like protein family member 11B

See identical proteins and their annotated locations for NP_956434.1

Status: PROVISIONAL

Source sequence(s)

BC044471

UniProtKB/Swiss-Prot

Q001T7, Q6P0U3, Q803I5

Related

ENSDARP00000003188.6, ENSDART00000015755.8

Conserved Domains (2) summary

smart00010
Location:22 → 187

small_GTPase; Small GTPase of the Ras superfamily; ill-defined subfamily

cd04146
Location:25 → 193

RERG_RasL11_like; Ras-related and Estrogen-Regulated Growth inhibitor (RERG) and Ras-like 11 (RasL11)-like families