plekha3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: plekha3provided by ZNC
Official Full Name: pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1252
See related: Ensembl:ENSDARG00000056601 AllianceGenome:ZFIN:ZDB-GENE-040426-1252
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:63749
Summary: Predicted to be involved in endosome organization; receptor recycling; and retrograde transport, endosome to Golgi. Predicted to be active in early endosome; recycling endosome; and trans-Golgi network. Orthologous to human PLEKHA3 (pleckstrin homology domain containing A3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (29756860..29768010, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (29509686..29520836, complement)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in endosome organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in receptor recycling	IBA Inferred from Biological aspect of Ancestor more info
involved_in retrograde transport, endosome to Golgi	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in early endosome	IBA Inferred from Biological aspect of Ancestor more info
is_active_in recycling endosome	IBA Inferred from Biological aspect of Ancestor more info
is_active_in trans-Golgi network	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: pleckstrin homology domain-containing family A member 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_201207.1 → NP_957501.1 pleckstrin homology domain-containing family A member 3

See identical proteins and their annotated locations for NP_957501.1

Status: PROVISIONAL

Source sequence(s)

BC055231

UniProtKB/TrEMBL

Q7SXV5

Related

ENSDARP00000073572.3, ENSDART00000079117.4

Conserved Domains (2) summary

cd01247
Location:1 → 100

PH_FAPP1_FAPP2; Four phosphate adaptor protein 1 and 2 Pleckstrin homology (PH) domain

pfam00169
Location:1 → 93

PH; PH domain