U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ift80 intraflagellar transport 80 homolog (Chlamydomonas) [ Danio rerio (zebrafish) ]

    Gene ID: 494082, updated on 3-Dec-2024

    Summary

    Official Symbol
    ift80provided by ZNC
    Official Full Name
    intraflagellar transport 80 homolog (Chlamydomonas)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041212-50
    See related
    Ensembl:ENSDARG00000038879 AllianceGenome:ZFIN:ZDB-GENE-041212-50
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fj11a06; zgc:101763
    Summary
    Acts upstream of or within several processes, including cilium assembly; convergent extension; and retina morphogenesis in camera-type eye. Predicted to be located in motile cilium. Predicted to be part of intraciliary transport particle B. Predicted to be active in centrosome and cilium. Is expressed in several structures, including eye; notochord; pectoral fin; pectoral fin bud; and pronephric duct. Used to study asphyxiating thoracic dystrophy; asphyxiating thoracic dystrophy 2; and ciliopathy. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy 2. Orthologous to human IFT80 (intraflagellar transport 80). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ift80 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (1494493..1534232, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (1529584..1569333, complement)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene karyopherin alpha 4 (importin alpha 3) Neighboring gene si:dkeyp-97b10.3 Neighboring gene chromosome 15 C3orf80 homolog Neighboring gene microRNA 15c Neighboring gene microRNA 16a Neighboring gene structural maintenance of chromosomes 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cilium IEA
    Inferred from Electronic Annotation
    more info
     
    located_in motile cilium IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    intraflagellar transport protein 80 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008625.1NP_001008625.1  intraflagellar transport protein 80 homolog

      See identical proteins and their annotated locations for NP_001008625.1

      Status: PROVISIONAL

      Source sequence(s)
      BC086735
      UniProtKB/TrEMBL
      A0A8M2BKN3, Q5PRA9
      Related
      ENSDARP00000056762.3, ENSDART00000056763.5
      Conserved Domains (3) summary
      COG2319
      Location:12310
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:61104
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:13287
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      1494493..1534232 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068213541.1XP_068069642.1  intraflagellar transport protein 80 homolog isoform X1

      UniProtKB/TrEMBL
      A0A8M2BKN3