psme1 proteasome activator subunit 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: psme1provided by ZNC
Official Full Name: proteasome activator subunit 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-991110-17
See related: Ensembl:ENSDARG00000002165 AllianceGenome:ZFIN:ZDB-GENE-991110-17
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fk89d05; wu:fk89d05
Summary: Predicted to enable endopeptidase activator activity. Predicted to be involved in positive regulation of endopeptidase activity; regulation of G1/S transition of mitotic cell cycle; and regulation of proteasomal protein catabolic process. Predicted to be part of proteasome activator complex. Predicted to be active in cytoplasm and nucleoplasm. Orthologous to human PSME1 (proteasome activator subunit 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 24

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	24	NC_007135.7 (12945869..12954482)
105	previous assembly	GRCz10 (GCF_000002035.5)	24	NC_007135.6 (12801450..12810063)

Chromosome 24 - NC_007135.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables endopeptidase activator activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of G1/S transition of mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of proteasomal protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleoplasm	IBA Inferred from Biological aspect of Ancestor more info
part_of proteasome activator complex	IEA Inferred from Electronic Annotation more info
part_of proteasome complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: proteasome activator complex subunit 1

Names: pA23-a; proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_131375.2 → NP_571450.1 proteasome activator complex subunit 1

See identical proteins and their annotated locations for NP_571450.1

Status: PROVISIONAL

Source sequence(s)

AF195052

UniProtKB/TrEMBL

F6NJT7, Q6DHV3, Q9PTH5

Related

ENSDARP00000012691.6, ENSDART00000005105.7

Conserved Domains (2) summary

pfam02251
Location:10 → 66

PA28_alpha; Proteasome activator pa28 alpha subunit

pfam02252
Location:103 → 240

PA28_beta; Proteasome activator pa28 beta subunit