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    gjc4a.1 gap junction protein gamma 4a.1 [ Danio rerio (zebrafish) ]

    Gene ID: 114404, updated on 2-Nov-2024

    Summary

    Official Symbol
    gjc4a.1provided by ZNC
    Official Full Name
    gap junction protein gamma 4a.1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-010619-1
    See related
    Ensembl:ENSDARG00000034207 AllianceGenome:ZFIN:ZDB-GENE-010619-1
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    gjc4a; cx44.2; fk18g12; wu:fk18g12; etID18867.6
    Summary
    Predicted to enable gap junction channel activity. Predicted to be involved in cell-cell signaling. Predicted to act upstream of or within cell communication. Predicted to be located in gap junction and plasma membrane. Predicted to be part of connexin complex. Is expressed in Kupffer's vesicle; ovary; and testis. [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    NEW
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    Genomic context

    See gjc4a.1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (21001455..21009814)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (18941233..18949540)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene insulin-like growth factor binding protein 2a Neighboring gene serine/threonine kinase 11 interacting protein Neighboring gene si:dkey-91f15.8 Neighboring gene gap junction protein gamma 4a.2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables gap junction channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell communication IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell-cell signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in anchoring junction IEA
    Inferred from Electronic Annotation
    more info
     
    part_of connexin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of connexin complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in gap junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    gap junction protein gamma 4a.1
    Names
    connexin 44.2
    gap junction protein gamma 4a

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131810.2NP_571885.2  gap junction protein gamma 4a.1

      See identical proteins and their annotated locations for NP_571885.2

      Status: PROVISIONAL

      Source sequence(s)
      BC045279
      UniProtKB/TrEMBL
      Q7ZU26
      Related
      ENSDARP00000044518.5, ENSDART00000044519.6
      Conserved Domains (3) summary
      smart00037
      Location:4375
      CNX; Connexin homologues
      smart01089
      Location:193259
      Connexin_CCC; Gap junction channel protein cysteine-rich domain
      pfam00029
      Location:2261
      Connexin; Connexin

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      21001455..21009814
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021476749.2XP_021332424.1  gap junction protein gamma 4a.1 isoform X1

      UniProtKB/TrEMBL
      A0A8M9Q5X3, F1QYI2
      Conserved Domains (1) summary
      pfam00029
      Location:2261
      Connexin; Connexin

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394633.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      234595..242655
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)